Dichloro(1,5-cyclooctadiene)platinum(II)
(1,5-Cyclooctadiene)platinum(II) dichloride, CAS 12080-32-9, is an organoplatinum compound with the molecular formula C8H12Cl2Pt. This platinum complex serves as a versatile catalyst in various organic transformations. It is particularly recognised for its utility in catalysing cyclization, coupling, and amination reactions, demonstrating significant potential in synthetic chemistry research and development.
- IUPAC
- (1,5-Cyclooctadiene)platinum dichloride,(1,5-Cyclooctadiene)platinum(II) dichloride,1,5-Cyclooctadienedichloroplatinum,NSC 239486,Pt(COD)Cl2
- Synonyms
- C8H12Cl2Pt(1,5-Cyclooctadiene)platinum dichloride(1,5-Cyclooctadiene)platinum(II) dichloride1,5-CyclooctadienedichloroplatinumNSC 239486Pt(COD)Cl2
Catalyst for Hydrogenative Cyclization
This platinum complex effectively catalyzes the hydrogenative cyclization of allenynes, a crucial step in the synthesis of complex organic molecules.
Stereoselective Tandem Reactions
It is employed in stereoselective tandem hydrosilylation-Hiyama coupling reactions, enabling the controlled formation of specific stereoisomers.
Amino Alkene Cyclohydroamination
The compound facilitates amino alkene cyclohydroamination, a valuable method for constructing nitrogen-containing heterocyclic compounds.
Hydrative Cyclization Reactions
It acts as a catalyst in hydrative cyclization reactions, contributing to efficient synthetic routes for various cyclic structures.
Direct Amination of Allylic Alcohols
This platinum complex enables the direct amination of allylic alcohols under mild conditions, offering a streamlined approach to amino alcohol synthesis.
Potential Anticancer Agent
Research suggests (1,5-Cyclooctadiene)platinum(II) dichloride may possess potential as an anticancer agent, indicating broader biological interest.
| Molecular weight | 374.16 |
|---|---|
| Empirical formula | C8H12Cl2Pt |
| Application | Catalyst for:• Hydrogenative cyclization of allenynes1• Stereoselective tandem hydrosilylation-Hiyama coupling reactions2• Amino alkene cyclohydroamination3• Hydrative cyclization reactions4• Direct amination of allylic alcohols under mild conditions5• Potential anticancer agent6 |
| Melting point | 285 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1,5-Cyclooctadiene)platinum(II) dichloride used for?
+
(1,5-Cyclooctadiene)platinum(II) dichloride is primarily used as a catalyst in organic synthesis for reactions such as hydrogenative cyclization of allenynes, stereoselective tandem hydrosilylation-Hiyama coupling, amino alkene cyclohydroamination, hydrative cyclization, and direct amination of allylic alcohols. It is also being investigated for its potential as an anticancer agent.
What is the CAS number and formula for this compound?
+
The CAS number is 12080-32-9, and its empirical formula (Hill notation) is C8H12Cl2Pt.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound for research and development purposes. The specific assay and purity will be detailed on the Certificate of Analysis provided with the product. We do not represent this product as USP, BP, or EP grade.
How should (1,5-Cyclooctadiene)platinum(II) dichloride be handled safely?
+
This compound is classified as a Warning under GHS and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid dust formation. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is this compound a controlled substance?
+
The provided data does not indicate that (1,5-Cyclooctadiene)platinum(II) dichloride is a controlled substance.
How is this chemical packed and exported?
+
Tech Serve Solutions handles the packing and export of chemicals with adherence to international shipping regulations. Detailed information regarding specific packaging for this product will be provided upon request.
How can I request a sample or quote for this product?
+
To request a sample or quote for (1,5-Cyclooctadiene)platinum(II) dichloride, please contact our sales department through the website or by phone, providing your specific requirements.
▶ Related products
Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis