(S)-Boc-2-(trifluoromethyl)-β-Homophe-OH
(S)-Boc-2-(trifluoromethyl)-β-Homophe-OH, CAS: 270065-74-2, is a specialised unnatural amino acid derivative with the molecular formula C16H20F3NO4 and a molecular weight of 347.33 g/mol. This compound is synthesised with a tert-butyloxycarbonyl (Boc) protecting group and a trifluoromethyl moiety, making it valuable in peptide chemistry and chemical synthesis. It serves as a building block for creating novel peptides and complex organic molecules.
- IUPAC
- (S)-3-(Boc-amino)-4-[2-(trifluoromethyl)phenyl]butyric acid,Boc-2-(trifluoromethyl)-L-β-homophenylalanine
Peptide Synthesis
Utilised as a non-canonical amino acid building block in solid-phase peptide synthesis (SPPS) and solution-phase methods. Its unique trifluoromethyl and beta-homo structure can introduce specific conformational constraints or properties into peptide chains.
Chemical Biology Research
Incorporated into biologically active peptides or peptidomimetics to probe protein-ligand interactions or develop new molecular probes. The trifluoromethyl group can influence lipophilicity and metabolic stability.
Medicinal Chemistry
Serves as a key intermediate in the synthesis of novel drug candidates. The incorporation of unnatural amino acids can lead to improved pharmacokinetic profiles, such as enhanced bioavailability or resistance to enzymatic degradation.
Organic Synthesis
A chiral building block for the construction of complex organic molecules beyond peptides. Its defined stereochemistry and functional groups are advantageous in asymmetric synthesis.
| Molecular weight | 347.33 |
|---|---|
| Empirical formula | C16H20F3NO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH used for?
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This compound is primarily used as a specialised building block in peptide synthesis, chemical biology research, medicinal chemistry, and general organic synthesis due to its unnatural amino acid structure featuring a trifluoromethyl group and Boc protection.
What is the CAS number and chemical formula for (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH?
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The CAS number is 270065-74-2, and the chemical formula is C16H20F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH with a purity of ≥98.0% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this chemical?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. It is classified under WGK 2 in Germany, indicating it is hazardous to water.
How is this chemical packed, shipped, or exported?
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Tech Serve Solutions packages and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant shipping and customs regulations for chemical substances.
How can I request a sample or obtain a quote?
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To request a sample or obtain a quotation for (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH, please contact our sales department through the website or by phone.
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