(S)-Boc-2-(trifluoromethyl)-β-Homophe-OH
(S)-Boc-2-(trifluoromethyl)-β-Homophe-OH (CAS: 270065-80-0) is a chiral building block with the molecular formula C16H20F3NO4 and a molecular weight of 347.33 g/mol. This unnatural amino acid derivative incorporates a trifluoromethyl group, making it valuable in chemical synthesis and peptide chemistry. It serves as a key intermediate in the development of novel peptidomimetics and pharmacologically active compounds, enabling the introduction of specific structural and electronic properties.
- IUPAC
- (S)-3-(Boc-amino)-4-[4-(trifluoromethyl)phenyl]butyric acid,Boc-4-(trifluoromethyl)-L-β-homophenylalanine
Peptide Synthesis
This compound is utilised as a non-natural amino acid in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the creation of peptides with enhanced stability, altered conformational preferences, and modified biological activities.
Drug Discovery and Development
As a specialised building block, it is employed in medicinal chemistry for the synthesis of novel drug candidates. The trifluoromethyl moiety can influence lipophilicity, metabolic stability, and binding affinity of potential pharmaceuticals.
Chemical Biology Research
Researchers use this molecule to explore structure-activity relationships and to design probes for biological systems. It enables the study of protein-protein interactions and the development of peptidomimetic therapeutics.
Organic Synthesis
It serves as a versatile intermediate in complex organic syntheses, providing a stereochemically defined scaffold for the construction of various target molecules with specific chiral centres.
| Molecular weight | 347.33 |
|---|---|
| Empirical formula | C16H20F3NO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH used for?
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(S)-Boc-2-(trifluoromethyl)-β-Homophe-OH is primarily used as a chiral building block in peptide synthesis, drug discovery, chemical biology research, and general organic synthesis due to its unique trifluoromethyl-substituted unnatural beta-amino acid structure.
What are the CAS number and formula for (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH?
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The CAS number for (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH is 270065-80-0, and its empirical formula is C16H20F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH with an assay of ≥98.0% (HPLC). This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling considerations for this compound?
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Handling (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany, indicating it is hazardous to water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions adheres to strict packaging and shipping regulations for the global export of chemicals, ensuring product integrity and compliance with international transport standards.
How can I request a sample or quote for (S)-Boc-2-(trifluoromethyl)-β-Homophe-OH?
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To request a sample or quote, please contact our sales department through the website or by phone, providing the product name and CAS number (270065-80-0).
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