(S)-(−)-Bay K8644

CAS 98625-26-4C16H15F3N2O4Cell Biology

(S)-(−)-Bay K8644 (CAS: 98625-26-4; Formula: C16H15F3N2O4) is a yellow solid with a molecular weight of 356.30 g/mol. It functions as a selective L-type calcium channel activator, exhibiting positive inotropic and chronotropic effects. This compound is a valuable tool in cardiovascular research, aiding studies into cardiac function, smooth muscle contraction, and related physiological processes. Available from Tech Serve Solutions in high purity for research applications.

IUPAC: S-(−)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester

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(S)-(−)-Bay K8644 (C16H15F3N2O4) — chemical structure, CAS 98625-26-4; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCalcium Channel ModulatorsCell BiologyInhibitors and ActivatorsIon Channels

01 /Applications

Cardiovascular Research

(S)-(−)-Bay K8644 serves as a vital pharmacological tool for investigating the mechanisms of L-type calcium channels. It is used to study the effects of calcium channel activation on cardiac contractility and heart rate in various experimental models.

Pharmacological Studies

This compound is employed in research to explore the physiological roles of voltage-gated calcium channels in smooth muscle tissues. Its ability to increase intracellular calcium levels aids in understanding calcium-dependent signaling pathways.

Neuroscience Research

Within neuroscience, (S)-(−)-Bay K8644 is utilized to examine the influence of L-type calcium channels on neuronal function and neurotransmitter release. It helps in elucidating the role of calcium influx in synaptic transmission and neuronal excitability.

02 /Properties

Molecular weight	356.30
Empirical formula	C16H15F3N2O4
Assay	≥98% (HPLC)
Form	solid
Colour	yellow
Solubility	H2O: slightly solubleethanol: soluble (Organic solutions are stable for at least 20 days at RT.)
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

98625-26-4

MDL number

MFCD00153769

05 /Additional specifications

Gene Information	human ... ADORA3(140)rat ... Adora1(29290), Adora2a(25369)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (S)-(−)-Bay K8644 used for?

(S)-(−)-Bay K8644 is primarily used as a research tool to study the function of L-type calcium channels, particularly in cardiovascular and neuroscience research, investigating its effects on cardiac contractility, heart rate, and neuronal function.

What are the CAS number and formula for (S)-(−)-Bay K8644?

The CAS number for (S)-(−)-Bay K8644 is 98625-26-4, and its molecular formula is C16H15F3N2O4.

What grade and purity does Tech Serve Solutions supply for (S)-(−)-Bay K8644?

Tech Serve Solutions supplies (S)-(−)-Bay K8644 with a purity of ≥98% (HPLC). This product is intended for research use and is not represented as USP, BP, or EP grade.

How should (S)-(−)-Bay K8644 be handled and stored?

Handle (S)-(−)-Bay K8644 with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, due to its irritant properties (H315, H319). Store the product at 2-8°C. In case of eye contact, rinse cautiously with water for several minutes and seek medical attention.

Is (S)-(−)-Bay K8644 a controlled substance?

The provided data does not indicate that (S)-(−)-Bay K8644 is a controlled substance.

How is (S)-(−)-Bay K8644 packed and exported?

(S)-(−)-Bay K8644 is supplied as a solid and exported by Tech Serve Solutions in compliance with international shipping regulations for chemicals.

How can I request a quote or sample for (S)-(−)-Bay K8644?

To request a quote or sample for (S)-(−)-Bay K8644, please contact our sales department through the website or by phone, providing your specific requirements.