(S)-(−)-2-Formamidosuccinic anhydride
(S)-(−)-2-Formamidosuccinic anhydride (CAS 33605-73-1), with the molecular formula C5H5NO4 and a molecular weight of 143.10 g/mol, is a chiral building block utilised in organic synthesis. This carboxylic acid anhydride is valuable for introducing specific stereochemistry in complex molecule construction. Its applications span across asymmetric synthesis and the development of advanced chemical intermediates.

Chiral Building Block
(S)-(−)-2-Formamidosuccinic anhydride serves as a key chiral building block in asymmetric synthesis. It enables the stereoselective construction of complex organic molecules, crucial for pharmaceutical and fine chemical development.
Organic Synthesis Reagent
As a functionalised anhydride, it participates in various organic transformations. Its structure allows for the introduction of specific functionalities and stereocentres into target molecules, aiding in synthetic strategies.
Development of Pharmaceutical Intermediates
This compound is employed in the synthesis pathways for creating advanced pharmaceutical intermediates. Its chiral nature is particularly important for developing stereochemically pure active pharmaceutical ingredients (APIs).
| Molecular weight | 143.10 |
|---|---|
| Empirical formula | C5H5NO4 |
| Assay | 90% |
| Optical activity | [α]20/D −53°, c = 1 in acetic acid |
| Melting point | 145-155 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Formamidosuccinic anhydride used for?
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(S)-(−)-2-Formamidosuccinic anhydride is primarily used as a chiral building block in asymmetric synthesis and for the development of organic intermediates, particularly in pharmaceutical chemistry.
What is the CAS number and chemical formula for (S)-(−)-2-Formamidosuccinic anhydride?
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The CAS number for (S)-(−)-2-Formamidosuccinic anhydride is 33605-73-1, and its chemical formula is C5H5NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-2-Formamidosuccinic anhydride with an assay of 90%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for (S)-(−)-2-Formamidosuccinic anhydride?
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This compound is classified as a warning irritant, with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
Is (S)-(−)-2-Formamidosuccinic anhydride available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-(−)-2-Formamidosuccinic anhydride.
How can I request a quote or sample for (S)-(−)-2-Formamidosuccinic anhydride?
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To request a quote or sample, please contact our sales team via the website or direct email, providing the product name and CAS number (33605-73-1).
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