(S)-(−)-2-Bromo-α-methylbenzyl alcohol

CAS 114446-55-8BrC6H4CH(CH3)OHChemical Synthesis

(S)-(−)-2-Bromo-α-methylbenzyl alcohol (CAS: 114446-55-8), with the molecular formula BrC₆H₄CH(CH₃)OH and a molar mass of 201.06 g/mol, is a chiral building block. It is primarily utilised in organic synthesis for the preparation of chiral boronic acids. These compounds are valuable reagents, particularly for determining the enantiomeric purity of diols using 1H-NMR spectroscopy.

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(S)-(−)-2-Bromo-α-methylbenzyl alcohol (BrC6H4CH(CH3)OH) — chemical structure, CAS 114446-55-8; Chemistry, fine chemical supplied by Tech Serve Solutions

AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Chiral Boronic Acid Synthesis

This compound serves as a key precursor in the synthesis of various chiral boronic acids. These derivatives are crucial reagents in advanced organic chemistry.

Enantiomeric Purity Determination

The chiral boronic acids derived from this alcohol are employed as analytical tools for determining the enantiomeric purity of diols. This is typically achieved through 1H-NMR spectroscopy.

Organic Synthesis Building Block

As an organic building block, it offers a chiral center and a reactive bromine atom, facilitating its incorporation into more complex molecular structures.

02 /Properties

Molecular weight	201.06
Linear formula	BrC6H4CH(CH3)OH
Assay	98%
Boiling point	128 °C/15 mmHg(lit.)
Optical activity	[α]30/D −54°, c = 1 in chloroform
Application	Used in the synthesis of chiral boronic acids, which serve as reagents for enantiomeric purity determination of diols by 1H-NMR.
Melting point	56-58 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

114446-55-8

MDL number

MFCD00004509

PubChem substance

24859653

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-2-Bromo-α-methylbenzyl alcohol used for?

This compound is used in organic synthesis, primarily for the preparation of chiral boronic acids, which are employed in the determination of enantiomeric purity of diols by 1H-NMR.

What are the CAS number and chemical formula?

The CAS number is 114446-55-8, and the chemical formula is BrC₆H₄CH(CH₃)OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-(−)-2-Bromo-α-methylbenzyl alcohol with an assay of 98%. This is considered a technical/research grade material and is not represented as USP, BP, or EP grade.

What are the safety considerations for handling this chemical?

This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Work should be conducted in a well-ventilated area. Refer to the Safety Data Sheet for full details.

Is this product available for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be shipped internationally. Please contact us for export details.

How can I request a sample or a quote?

To request a sample or a quote for (S)-(−)-2-Bromo-α-methylbenzyl alcohol, please use the 'Request a Quote' or 'Contact Us' form on our website, providing your specific requirements.