(S)-(+)-1-Cbz-3-pyrrolidinol
(S)-(+)-1-Cbz-3-pyrrolidinol (CAS: 100858-32-0, C12H15NO3) is a chiral pyrrolidine derivative widely employed in asymmetric synthesis and organic chemistry. With a molecular weight of 221.25 g/mol, it serves as a valuable chiral building block for the construction of complex molecules. Its specific stereochemistry makes it particularly useful in the development of pharmaceuticals and other enantiomerically pure compounds, contributing to advancements in medicinal chemistry and materials science.
- IUPAC
- (S)-N-Z-3-Pyrrolidinol,(S)-1-Benzyloxycarbonyl-3-pyrrolidinol,(S)-1-Carbobenzoxy-3-pyrrolidinol
- Synonyms
- (S)-N-Z-3-Pyrrolidinol(S)-1-Benzyloxycarbonyl-3-pyrrolidinol(S)-1-Carbobenzoxy-3-pyrrolidinol
Chiral Building Block in Organic Synthesis
Serves as a key intermediate in the stereoselective synthesis of various organic compounds, particularly those with pyrrolidine rings. Its defined stereochemistry is crucial for controlling the absolute configuration of target molecules.
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where specific chirality is essential for biological activity and efficacy. It aids in the development of enantiomerically pure drugs.
Asymmetric Synthesis
Applied in reactions requiring a chiral auxiliary or starting material to induce asymmetry, leading to the formation of enantiomerically enriched products. This is vital for creating stereospecific catalysts and reagents.
Research and Development
A fundamental reagent in academic and industrial research laboratories for exploring novel synthetic routes and developing new chemical entities. Its availability supports innovation in chemical sciences.
| Molecular weight | 221.25 |
|---|---|
| Empirical formula | C12H15NO3 |
| Assay | 95% |
| Optical activity | [α]20/D +21°, c = 1 in chloroform |
| Melting point | 71-77 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-1-Cbz-3-pyrrolidinol used for?
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(S)-(+)-1-Cbz-3-pyrrolidinol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals. It is valuable for constructing complex, enantiomerically pure molecules.
What are the CAS number and formula for (S)-(+)-1-Cbz-3-pyrrolidinol?
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The CAS number is 100858-32-0, and its empirical formula is C12H15NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-1-Cbz-3-pyrrolidinol with an assay of 95%. This product is supplied for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should (S)-(+)-1-Cbz-3-pyrrolidinol be handled safely?
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Handle with extreme care. This compound is toxic if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation (H301-H315-H319-H335). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator, is essential. Ensure adequate ventilation.
Is this product available for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals like (S)-(+)-1-Cbz-3-pyrrolidinol to research institutions and industries worldwide.
How can I request a sample or quote?
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To request a sample or a quote for (S)-(+)-1-Cbz-3-pyrrolidinol, please contact our sales department through the details provided on our website.
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