(S)-(+)-1-Cbz-3-aminopyrrolidine
(S)-(+)-1-Cbz-3-aminopyrrolidine (CAS: 122536-72-5) is a chiral heterocyclic compound with the molecular formula C12H16N2O2 and a molecular weight of 220.27 g/mol. This enantiomerically pure building block is instrumental in asymmetric synthesis, enabling the creation of stereospecific molecules. Its protected amine functionality makes it a valuable intermediate in the development of pharmaceuticals and complex organic compounds, particularly where precise stereochemistry is critical.
- IUPAC
- (S)-1-Benzyloxycarbonyl-3-aminopyrrolidine
Chiral Building Block
Serves as a fundamental chiral synthon in the asymmetric synthesis of complex organic molecules. Its pyrrolidine core and protected amine group allow for stereoselective functionalization in drug discovery and development.
Pharmaceutical Intermediates
Used in the synthesis pathways of various pharmaceutical agents where specific stereoisomers are required for therapeutic efficacy. It contributes to the construction of pharmacologically active heterocyclic scaffolds.
Asymmetric Synthesis
Facilitates the creation of enantiomerically enriched compounds through stereocontrolled reactions. Its defined stereocenter is critical for developing chiral drugs and other fine chemicals with specific biological activities.
Organic Synthesis Reagent
A versatile reagent in general organic synthesis for introducing a chiral pyrrolidine moiety. It is employed in multistep syntheses requiring precise control over molecular architecture and stereochemistry.
| Molecular weight | 220.27 |
|---|---|
| Empirical formula | C12H16N2O2 |
| Assay | 97% |
| Boiling point | 315 °C |
| Density | 1.155 g/mL at 25 °C |
| Refractive index | n20/D 1.548 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-1-Cbz-3-aminopyrrolidine used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals. Its defined stereochemistry is crucial for creating stereospecific molecules and active pharmaceutical ingredients.
What are the CAS number and molecular formula for (S)-(+)-1-Cbz-3-aminopyrrolidine?
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The CAS number is 122536-72-5 and the molecular formula is C12H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-1-Cbz-3-aminopyrrolidine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling (S)-(+)-1-Cbz-3-aminopyrrolidine?
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This compound is classified as harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used.
Is (S)-(+)-1-Cbz-3-aminopyrrolidine controlled or scheduled?
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The provided data does not indicate that (S)-(+)-1-Cbz-3-aminopyrrolidine is a controlled or scheduled substance.
How is (S)-(+)-1-Cbz-3-aminopyrrolidine packed and shipped?
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Tech Serve Solutions exports chemicals globally, ensuring appropriate packaging for safe transport according to international regulations. Specific packing details are available upon request.
How can I request a quote or sample for (S)-(+)-1-Cbz-3-aminopyrrolidine?
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To request a quote or sample, please contact our sales department through the TSS website or by calling our dedicated line. Our team will be happy to assist you with your inquiry.
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