(S)-(−)-2-Bromo-3-methylbutyric acid
(S)-(−)-2-Bromo-3-methylbutyric acid (CAS 26782-75-2) is a chiral organic building block with the linear formula (CH3)2CHCH(Br)CO2H and a molecular weight of 181.03 g/mol. This bromoacid is utilised in asymmetric synthesis and for the preparation of specific peptide derivatives and peptidomimetics. It is supplied by Tech Serve Solutions with an assay of 96%.
- IUPAC
- (S)-2-Bromoisovaleric acid
- Synonyms
- (S)-2-Bromoisovaleric acid
Chiral Building Block for Organic Synthesis
This compound serves as a valuable chiral building block in asymmetric synthesis. Its structure allows for stereoselective incorporation into more complex molecules.
Preparation of Ferroelectric Liquid Crystal Derivatives
It has been employed in the synthesis of ferroelectric liquid crystal derivatives, contributing to the development of advanced materials.
Synthesis of Peptide Analogues
The bromoacid is used in the preparation of proline-valine pseudo dipeptides and β-turn peptidomimetics, which are important in medicinal chemistry research.
| Molecular weight | 181.03 |
|---|---|
| Linear formula | (CH3)2CHCH(Br)CO2H |
| Assay | 96% |
| Boiling point | 90-100 °C/0.5 mmHg(lit.) |
| Optical activity | [α]22/D −21°, c = 37 in benzene |
| Application | Ferroelectric liquid crystal derivatives,1 proline-valine pseudo dipeptides which are potent inhibitors of α-chymotrypsin,2 and β-turn peptidomimetics have been prepared using this bromoacid.3 |
| Melting point | 39-44 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Bromo-3-methylbutyric acid used for?
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It is used as a chiral building block in asymmetric synthesis, and for the preparation of ferroelectric liquid crystal derivatives and specific peptide analogues such as proline-valine pseudo dipeptides and β-turn peptidomimetics.
What is the CAS number and chemical formula for (S)-(−)-2-Bromo-3-methylbutyric acid?
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The CAS number is 26782-75-2 and the linear chemical formula is (CH3)2CHCH(Br)CO2H.
What grade and purity does Tech Serve Solutions supply for (S)-(−)-2-Bromo-3-methylbutyric acid?
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Tech Serve Solutions supplies this product with an assay of 96%. We do not represent it as USP, BP, or EP grade.
What are the primary safety hazards associated with (S)-(−)-2-Bromo-3-methylbutyric acid?
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(S)-(−)-2-Bromo-3-methylbutyric acid is classified as Danger. It is harmful if swallowed, in contact with skin, and if inhaled, and causes severe skin burns and eye damage. Appropriate personal protective equipment, including gloves, eyeshields, and respiratory protection, must be used during handling.
How is (S)-(−)-2-Bromo-3-methylbutyric acid packed, shipped, and exported?
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This chemical is shipped as UN 3261, Class 8, Packing Group II, reflecting its hazardous nature. TSS ensures compliant packaging and export documentation for global distribution.
How can I request a quote or sample of (S)-(−)-2-Bromo-3-methylbutyric acid?
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Please contact our sales team via the website or direct email to request a quotation or a sample.
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