(S)-(−)-2-Chloropropionic acid
(S)-(−)-2-Chloropropionic acid (CAS 29617-66-1), with the molecular formula CH3CH(Cl)CO2H and a molecular weight of 108.52 g/mol, is a chiral carboxylic acid. It is an essential building block in asymmetric synthesis, frequently employed in the creation of complex organic molecules and pharmaceutical intermediates. Its specific stereochemistry makes it valuable for reactions requiring precise control over molecular architecture.
- IUPAC
- (S)-(−)-2-Chloropropanoic acid,L-α-Chloropropionic acid
- Synonyms
- L-α-Chloropropionic acid
Chiral Building Block
This compound serves as a key chiral synthon in the synthesis of enantiomerically pure pharmaceuticals and agrochemicals. Its defined stereocenter allows for stereoselective transformations, leading to products with desired biological activity.
Asymmetric Synthesis
Utilised in asymmetric synthesis to introduce chirality into target molecules. It is a valuable precursor for developing new chiral ligands, catalysts, or active pharmaceutical ingredients (APIs).
Organic Synthesis Intermediate
As a functionalised carboxylic acid, it participates in a variety of organic reactions, including esterification, amidation, and reduction, facilitating the construction of diverse molecular scaffolds.
| Molecular weight | 108.52 |
|---|---|
| Linear formula | CH3CH(Cl)CO2H |
| Assay | 99% |
| Boiling point | 77 °C/10 mmHg(lit.) |
| Density | 1.249 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4347(lit.) |
| Optical activity | [α]25/D −14°, neat |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 106 °C / 222.8 °F |
| Transport (UN / ADR) | UN 2511 8 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 21/22-35-48/22 |
| Safety statements (S) | 23-26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Chloropropionic acid used for?
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(S)-(−)-2-Chloropropionic acid is primarily used as a chiral building block in asymmetric synthesis for the preparation of complex organic molecules, including pharmaceutical intermediates and agrochemicals.
What are the CAS number and formula for (S)-(−)-2-Chloropropionic acid?
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The CAS number for (S)-(−)-2-Chloropropionic acid is 29617-66-1, and its linear formula is CH3CH(Cl)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-2-Chloropropionic acid with an assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(−)-2-Chloropropionic acid be handled safely?
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Handling requires caution due to its corrosive nature and potential health hazards. Always use appropriate personal protective equipment, including gloves, goggles, and a suitable respirator, and handle in a well-ventilated area. Refer to the safety data sheet for comprehensive handling information.
Is (S)-(−)-2-Chloropropionic acid a controlled substance?
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The provided data does not indicate that (S)-(−)-2-Chloropropionic acid is a controlled substance.
How is (S)-(−)-2-Chloropropionic acid packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions exports chemicals internationally, adhering to all relevant shipping regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a quote or sample for (S)-(−)-2-Chloropropionic acid?
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Please contact our sales team through the website or by phone to request a quotation or to arrange for a sample.
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