(S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid
(S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid (CAS: 21641-92-9) is a chiral organic building block with the molecular formula C6H12O3 and a molecular weight of 132.16 g/mol. This carboxylic acid is a valuable precursor in asymmetric synthesis, primarily used for constructing chiral tert-butyl substituted α-lactams, diols, and α-hydroxyketones. Available with a purity of 97%, it is supplied by Tech Serve Solutions for research and development purposes.
- Synonyms
- (CH3)3CCH(OH)CO2H
Chiral Lactam Synthesis
Serves as a key chiral building block for the synthesis of tert-butyl substituted α-lactams, offering stereochemical control in the formation of complex heterocyclic structures.
Diol and α-Hydroxyketone Preparation
Utilised as a precursor for the asymmetric synthesis of specific diols and α-hydroxyketones, contributing to the development of enantiomerically pure compounds.
Asymmetric Synthesis Intermediate
A versatile intermediate in organic synthesis, particularly valuable for introducing chirality and tert-butyl groups into target molecules.
| Molecular weight | 132.16 |
|---|---|
| Linear formula | (CH3)3CCH(OH)CO2H |
| Assay | 97% |
| Optical activity | [α]20/D −64±5°, c = 1 in H2O/molybdate |
| Application | Building block for chiral tert-butyl substituted α-lactams,1 diols,2 and α-hydroxyketones.3 |
| Melting point | 48-50 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid used for?
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This compound is used as a chiral building block in asymmetric synthesis for preparing tert-butyl substituted α-lactams, diols, and α-hydroxyketones.
What are the CAS number and formula for (S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid?
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The CAS number is 21641-92-9 and the linear formula is (CH3)3CCH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid with an assay of 97%. This is a research grade material and is not represented as USP, BP, or EP.
How should (S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid be handled?
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It is classified as a Warning under GHS. Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation, as it may cause skin, eye, and respiratory irritation (H315, H319, H335).
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid.
How can I request a sample or quote?
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To request a sample or quote for (S)-(−)-2-Hydroxy-3,3-dimethylbutyric acid, please contact our sales team through the website or by phone.
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