(R)-H8-BINAP
(R)-H8-BINAP (CAS: 139139-86-9) is a chiral phosphine ligand with the molecular formula C44H40P2 and a molecular weight of 630.74 g/mol. This compound is integral to asymmetric synthesis, particularly in catalytic reactions requiring stereochemical control. It is widely employed as a privileged ligand in various chemical transformations, facilitating the production of enantiomerically pure compounds. TSS supplies this critical reagent for advanced chemical research and development.
- IUPAC
- (R)-(+)-2,2′-Bis(diphenylphospino)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl,[(1R)-5,5′,6,6′,7,7′,8,8′-octahydro-[1,1′-binaphthalene]-2,2′-diyl]bis[diphenylphosphine]
Asymmetric Catalysis
(R)-H8-BINAP serves as a key chiral ligand in transition metal catalysis for asymmetric reactions. Its unique structure enables high enantioselectivity in various bond-forming processes, crucial for pharmaceutical intermediate synthesis.
Homogeneous Catalysis
This privileged ligand is extensively used in homogeneous catalysis, facilitating reactions such as asymmetric hydrogenation, isomerisation, and C-C bond formation with remarkable efficiency and stereocontrol.
Synthesis of Enantiopure Compounds
It is instrumental in the synthesis of chiral molecules where precise stereochemistry is paramount. Applications include the development of active pharmaceutical ingredients and fine chemicals requiring specific enantiomers.
Research and Development
As a valuable tool in organic synthesis, (R)-H8-BINAP is widely utilized in academic and industrial R&D settings to explore new synthetic methodologies and develop novel chiral catalysts.
| Molecular weight | 630.74 |
|---|---|
| Empirical formula | C44H40P2 |
| Assay | ≥94% |
| Optical activity | [α]20/D +74°, c = 0.5 in toluene |
| Application | Takasago Ligands and Complexes for Asymmetric Reactions |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-H8-BINAP primarily used for?
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(R)-H8-BINAP is primarily used as a chiral ligand in asymmetric synthesis and homogeneous catalysis to produce enantiomerically pure compounds.
What is the CAS number and molecular formula for (R)-H8-BINAP?
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The CAS number for (R)-H8-BINAP is 139139-86-9, and its molecular formula is C44H40P2.
What grade and purity does Tech Serve Solutions supply for (R)-H8-BINAP?
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Tech Serve Solutions supplies (R)-H8-BINAP with an assay of ≥94%. This product is supplied for research and technical use and is not represented as USP, BP, or EP grade.
How should (R)-H8-BINAP be handled safely?
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(R)-H8-BINAP is classified as a Warning. It causes skin irritation (H315) and serious eye irritation (H319). Handle with appropriate personal protective equipment, including gloves and eye protection, and ensure good ventilation. In case of contact, follow precautionary statements (P305 + P351 + P338).
Is (R)-H8-BINAP suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (R)-H8-BINAP, and can facilitate international shipping.
How can I request a quote or sample for (R)-H8-BINAP?
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To request a quote or sample of (R)-H8-BINAP, please contact our sales team through the website or call our customer service line.
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