(R)-Fmoc-Nip-OH
(R)-Fmoc-Nip-OH (CAS: 193693-67-3) is a chiral piperidine derivative with the molecular formula C21H21NO4 and a molecular weight of 351.40. This unnatural amino acid derivative is primarily utilised in peptide chemistry and chemical synthesis. It serves as a valuable building block for the construction of complex peptides and peptidomimetics, particularly where the incorporation of a nipecotic acid moiety is required. Tech Serve Solutions supplies this compound for research and development purposes.
- IUPAC
- (R)-N-Fmoc-piperidine-3-carboxylic acid,(R)-Fmoc-nipecotic acid
- Synonyms
- (R)-N-Fmoc-piperidine-3-carboxylic acid(R)-Fmoc-nipecotic acid
Peptide Synthesis
(R)-Fmoc-Nip-OH is an essential unnatural amino acid derivative used in solid-phase and solution-phase peptide synthesis. It allows for the introduction of a piperidine-3-carboxylic acid residue into peptide chains, enabling the study of peptide structure-activity relationships and the development of novel peptide-based therapeutics.
Chemical Synthesis
As a versatile chiral building block, this compound finds application in various complex organic synthesis projects. Its unique structure can be incorporated into diverse molecular architectures for research in medicinal chemistry and materials science.
Chemical Biology Research
The incorporation of (R)-Fmoc-Nip-OH into peptides or other biomolecules can provide probes for studying biological systems. This aids in understanding protein-ligand interactions and developing novel diagnostic or therapeutic agents.
| Molecular weight | 351.40 |
|---|---|
| Empirical formula | C21H21NO4 |
| Assay | ≥99.0% (HPLC) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Fmoc-Nip-OH used for?
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(R)-Fmoc-Nip-OH is used as a building block in peptide synthesis, chemical synthesis, and chemical biology research, particularly for incorporating unnatural amino acid structures.
What is the CAS number and formula for (R)-Fmoc-Nip-OH?
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The CAS number is 193693-67-3, and the empirical formula is C21H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Fmoc-Nip-OH with an assay of ≥99.0% (HPLC). This compound is intended for research and development use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should (R)-Fmoc-Nip-OH be handled and stored?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, due to hazards H315 (skin irritation), H319 (eye irritation), and H335 (respiratory irritation). Store at 2-8°C.
Is (R)-Fmoc-Nip-OH a controlled substance?
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The provided data does not indicate that (R)-Fmoc-Nip-OH is a controlled substance.
How are products from Tech Serve Solutions packed and shipped?
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Products are carefully packed and exported by Tech Serve Solutions, adhering to all necessary shipping regulations for chemical compounds.
How can I request a sample or quote for (R)-Fmoc-Nip-OH?
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To request a sample or quote, please contact our sales department through the website or by direct inquiry, providing the product name and CAS number.
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