(R)-Glycerol 1-(p-toluenesulfonate)
(R)-Glycerol 1-(p-toluenesulfonate) (CAS: 41274-09-3, Formula: C10H14O5S) is a chiral organic building block with a molecular weight of 246.28. This compound serves as a valuable intermediate in asymmetric synthesis and general chemical synthesis. Its structure, featuring a chiral glycerol backbone derivatized with a tosylate group, makes it a versatile starting material for creating complex molecules with defined stereochemistry. Tech Serve Solutions supplies this reagent for research and development purposes.
- IUPAC
- (R)-2,3-Dihydroxypropyl p-toluenesulfonate,(R)-3-Tosyloxy-1,2-propanediol,sn-Glyceryl 1-(p-toluenesulfonate)
- Synonyms
- (R)-2,3-Dihydroxypropyl p-toluenesulfonate(R)-3-Tosyloxy-1,2-propanediolsn-Glyceryl 1-(p-toluenesulfonate)

Chiral Synthesis Intermediate
Utilised as a key building block in the stereoselective synthesis of complex organic molecules, particularly where precise chirality is required.
Pharmaceutical Precursor
Can be employed in the multi-step synthesis of pharmaceutical active ingredients (APIs) or their advanced intermediates, contributing to stereochemical control.
Asymmetric Catalysis Research
Serves as a chiral auxiliary or precursor in the development and study of asymmetric catalytic systems.
Organic Building Block
Provides a functionalised chiral three-carbon unit for incorporation into diverse organic structures in synthetic chemistry.
| Molecular weight | 246.28 |
|---|---|
| Empirical formula | C10H14O5S |
| Assay | 95% (TLC) |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Glycerol 1-(p-toluenesulfonate) used for?
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(R)-Glycerol 1-(p-toluenesulfonate) is primarily used as a chiral building block and intermediate in asymmetric synthesis and general organic chemical synthesis, including the preparation of pharmaceutical intermediates.
What are the CAS number and formula for (R)-Glycerol 1-(p-toluenesulfonate)?
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The CAS number is 41274-09-3, and the empirical formula (Hill notation) is C10H14O5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Glycerol 1-(p-toluenesulfonate) with an assay of 95% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the primary safety concerns when handling (R)-Glycerol 1-(p-toluenesulfonate)?
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This compound is classified under GHS07 with a 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is (R)-Glycerol 1-(p-toluenesulfonate) stored and shipped?
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The recommended storage temperature is −20°C. For export and shipping, appropriate packaging and handling procedures are followed to maintain product integrity and comply with regulations.
How can I request a sample or quote for (R)-Glycerol 1-(p-toluenesulfonate)?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales department through our website or by phone, providing your contact details and the product CAS number (41274-09-3).
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