2-Amino-2-methyl-1,3-propanediol
2-Amino-2-methyl-1,3-propanediol (CAS: 115-69-5), with the linear formula (HOCH2)2C(NH2)CH3 and a molecular weight of 105.14 g/mol, is a versatile amino alcohol. It is commonly employed as a buffer component in biochemical applications, particularly in electrophoresis systems for protein separation. Its utility extends to isotachophoresis and enzyme activity assays, making it a valuable reagent in research and diagnostics.
- IUPAC
- AMPD,Ammediol
- Synonyms
- (HOCH2)2C(NH2)CH3AMPDAmmediol
Buffer Component in Electrophoresis
This compound serves as an effective buffer in SDS-gradient gel electrophoresis, facilitating the separation of polypeptides within a broad molecular weight range. It is also utilised as a spacer in the isotachophoresis of proteins.
Enzyme Activity Assays
2-Amino-2-methyl-1,3-propanediol is used as a buffer for the accurate determination of enzymatic activities, including alkaline phosphatase. Its buffering capacity ensures stable pH conditions crucial for reliable assay results.
Organic Synthesis Building Block
As an organic building block, this amino alcohol offers reactive functional groups suitable for various chemical syntheses. It can be incorporated into more complex molecular structures for research and development purposes.
| Molecular weight | 105.14 |
|---|---|
| Linear formula | (HOCH2)2C(NH2)CH3 |
| Assay | ≥97.0% (GC) |
| Boiling point | 151 °C/10 mmHg(lit.) |
| Solubility | water: soluble105.1 g/L |
| pH | 10.5-11.5 (25 °C, 1 M in H2O) |
| Vapour pressure | ~10 mmHg (152 °C) |
| Melting point | 100-110 °C(lit.)100-110 °C |
| Vapour density | 3.63 (vs air) |
| Loss on drying | ~1% loss on drying |
| Impurities tested | insoluble matter, passes filter test |
| Application | Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000.3 Used as a spacer in isotachophoresis of proteins.1,2 Also used as a buffer for the determination of alkaline phosphatase activity.4 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Anion traces | carbonate (CO32-): ≤1000 mg/kgchloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Uv Absorption | λ: 260 nm Amax: 0.05λ: 280 nm Amax: 0.03 |
|---|---|
| Useful Ph Range | 7.8 - 9.7 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-2-methyl-1,3-propanediol used for?
+
It is primarily used as a buffer component in electrophoresis systems, for isotachophoresis of proteins, and in enzyme activity assays, such as for alkaline phosphatase.
What is the CAS number and formula for 2-Amino-2-methyl-1,3-propanediol?
+
The CAS number is 115-69-5 and the linear formula is (HOCH2)2C(NH2)CH3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Amino-2-methyl-1,3-propanediol with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should 2-Amino-2-methyl-1,3-propanediol be handled?
+
This compound is a warning-level hazard, causing skin (H315), eye (H319), and respiratory irritation (H335). Use a dust mask (N95), eyeshields, and gloves. Ensure good ventilation. Refer to the Safety Data Sheet for full details.
Is 2-Amino-2-methyl-1,3-propanediol a controlled substance?
+
Based on the provided data, 2-Amino-2-methyl-1,3-propanediol is not listed as a controlled substance.
How is 2-Amino-2-methyl-1,3-propanediol packed, shipped, and exported?
+
2-Amino-2-methyl-1,3-propanediol is packed according to standard chemical handling procedures for safe transport and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for 2-Amino-2-methyl-1,3-propanediol?
+
Please contact our sales team through the website or by phone to request a quote or a sample of 2-Amino-2-methyl-1,3-propanediol.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis