Maleimide
Maleimide (CAS 541-59-3, C4H3NO2) is a cyclic imide and organic building block with a molecular weight of 97.07 g/mol. It serves as a key intermediate in chemical synthesis. This compound is primarily utilised in research and development settings, particularly for the functionalisation of materials and in bioconjugation techniques due to its reactive double bond.
- IUPAC
- 2,5-Pyrroledione
Bioconjugation and Material Functionalisation
Maleimide is frequently employed to covalently attach molecules, such as proteins or peptides, to surfaces or other molecules. Its reactivity with thiols makes it ideal for creating stable linkages in biochemical assays and diagnostics.
Organic Synthesis Intermediate
As a versatile building block, maleimide participates in various organic reactions, including Diels-Alder cycloadditions. It is used in the synthesis of more complex heterocyclic compounds and pharmaceutical intermediates.
Polymer Chemistry
Maleimide derivatives can be incorporated into polymers to modify their properties or to introduce cross-linking capabilities. This is valuable in the development of advanced materials with tailored characteristics.
| Molecular weight | 97.07 |
|---|---|
| Empirical formula | C4H3NO2 |
| Assay | 99% |
| Application | The maleimide-functionalized silica beads were used to immobilize the bovine serum albumin (BSA)-boronic acid (BA) conjugates1. |
| Melting point | 91-93 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2923 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-34-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Maleimide used for?
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Maleimide is used as a building block in organic synthesis, for bioconjugation, and in the functionalisation of materials and polymers.
What is the CAS number and formula for Maleimide?
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The CAS number for Maleimide is 541-59-3 and its empirical formula is C4H3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Maleimide with an assay of 99%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should Maleimide be handled safely?
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Maleimide is a dangerous substance that causes severe skin burns and eye damage and may cause an allergic skin reaction. It is toxic if swallowed. Always wear appropriate personal protective equipment, including eyeshields, face shields, gloves, and a respirator. Handle only in a well-ventilated area or under a fume hood. Refer to the safety data sheet for comprehensive handling information.
Is Maleimide a controlled substance?
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The provided data does not indicate that Maleimide is a controlled substance.
How is Maleimide packed, shipped, and exported?
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Maleimide is carefully packed according to international shipping regulations and is available for export worldwide by Tech Serve Solutions.
How can I request a sample or quote for Maleimide?
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To request a sample or a quote for Maleimide, please contact our sales team through the website or by phone.
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