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(R)-N-Boc-1-oxa-4-azaspiro[4.5]decane-3-carboxaldehyde

CAS 171623-07-7C14H23NO4Chemical Synthesis

(R)-N-Boc-1-oxa-4-azaspiro[4.5]decane-3-carboxaldehyde (CAS: 171623-07-7) is a chiral heterocyclic building block with the molecular formula C14H23NO4 and a molecular weight of 269.34 g/mol. Supplied with an assay of 95%, this compound is crucial in asymmetric synthesis and chemical research. Its specific stereochemistry and functional groups make it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and fine chemical industries.

IUPAC
(3R)-3-Formyl-1-oxa-4-azaspiro[4.5]decane-4-carboxylic acid, 1,1-dimethylethyl ester,(R)-Garner′s Aldehyde analog,tert-Butyl (3R)-3-formyl-1-oxa-4-azaspiro[4.5]decane-4-carboxylate
Synonyms
(3R)-3-Formyl-1-oxa-4-azaspiro[4.5]decane-4-carboxylic acid, 1,1-dimethylethyl ester(R)-Garner′s Aldehyde analogtert-Butyl (3R)-3-formyl-1-oxa-4-azaspiro[4.5]decane-4-carboxylate
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(R)-N-Boc-1-oxa-4-azaspiro[4.5]decane-3-carboxaldehyde (C14H23NO4) — chemical structure, CAS 171623-07-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksOthers
01 /Applications

Asymmetric Synthesis

This chiral aldehyde serves as a key building block in enantioselective synthesis, enabling the creation of stereochemically defined molecules. Its rigid spirocyclic structure aids in controlling stereochemical outcomes during synthetic transformations.

Pharmaceutical Intermediate

The compound's heterocyclic nature and chiral centre make it a versatile intermediate in the development of novel pharmaceutical agents. It can be incorporated into synthetic routes targeting biologically active compounds.

Chemical Research

Utilised in academic and industrial research laboratories for exploring new synthetic methodologies and developing novel chemical entities. Its aldehyde functionality allows for a variety of subsequent chemical reactions.

Heterocyclic Chemistry

As a spirocyclic oxa-azaspiro decane derivative, it provides a unique scaffold for the synthesis of complex heterocyclic systems with potential applications in medicinal chemistry.

02 /Properties
Molecular weight269.34
Empirical formulaC14H23NO4
Assay95%
Optical activity[α]22/D +69.0°, c = 1% in chloroform
Storage temperature−20°C
Melting point53-58 °C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Environmental hazard (GHS09)
Environmental hazard
Danger

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation
  • H400Very toxic to aquatic life

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P273Avoid release to the environment
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Transport (UN / ADR)UN 3077 9 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn,N
Risk statements (R)22-37/38-41-50
Safety statements (S)26-39-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
171623-07-7
MDL number
MFCD24849718
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-N-Boc-1-oxa-4-azaspiro[4.5]decane-3-carboxaldehyde used for?

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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and other fine chemicals.

What are the CAS number and formula for this chemical?

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The CAS number is 171623-07-7 and the empirical formula is C14H23NO4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this chemical with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety considerations for handling this compound?

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This compound is classified with Danger signal word and carries hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), H335 (May cause respiratory irritation), and H400 (Very toxic to aquatic life). Always handle with appropriate personal protective equipment, including eye protection, gloves, and in a well-ventilated area or fume hood. Avoid release to the environment.

How is this product packed, shipped, and exported?

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Products are carefully packed according to international shipping regulations. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.

How can I request a sample or quote?

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Please contact our sales team via the website or email to request a sample or a formal quotation for (R)-N-Boc-1-oxa-4-azaspiro[4.5]decane-3-carboxaldehyde.

Need (R)-N-Boc-1-oxa-4-azaspiro[4.5]decane-3-carboxaldehyde in a specific grade or volume?