(R)-N-Boc-2-phenylpyrrolidine
(R)-N-Boc-2-phenylpyrrolidine (CAS: 174311-02-5), with the molecular formula C15H21NO2 and a molecular weight of 247.33 g/mol, is a valuable chiral building block. This tert-butyl ester derivative of (R)-2-phenylpyrrolidine is frequently employed in asymmetric synthesis and complex chemical manufacturing processes requiring stereochemical control. Its specific optical activity is [α]22/D +85.0° (c = 1 in acetone).
- IUPAC
- (R)-2-Phenyl-1-pyrrolidinecarboxylic acid tert-butyl ester
Asymmetric Synthesis
This chiral pyrrolidine derivative serves as a key intermediate or chiral auxiliary in asymmetric synthesis, enabling the enantioselective construction of complex molecules. Its defined stereochemistry is crucial for directing the formation of new chiral centres.
Pharmaceutical Intermediate
The compound's structure lends itself to the synthesis of various pharmaceutical agents where specific stereoisomers are required for biological activity. It can be incorporated into drug discovery and development pipelines.
Heterocyclic Chemistry
As a substituted pyrrolidine, it is a useful building block in heterocyclic chemistry for the synthesis of novel ring systems. The phenyl and Boc-protected amine functionalities offer versatile reaction sites.
| Molecular weight | 247.33 |
|---|---|
| Empirical formula | C15H21NO2 |
| Optical activity | [α]22/D +85.0°, c = 1 in acetone |
| Melting point | 61-66 °C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-N-Boc-2-phenylpyrrolidine primarily used for?
+
(R)-N-Boc-2-phenylpyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the chemical and pharmaceutical industries.
What are the CAS number and molecular formula for this compound?
+
The CAS number is 174311-02-5, and the molecular formula is C15H21NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-N-Boc-2-phenylpyrrolidine typically as a research or technical grade chemical. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.
What are the main safety hazards associated with (R)-N-Boc-2-phenylpyrrolidine?
+
This compound is classified as acutely toxic if swallowed (GHS06, Danger, H301). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, is essential when handling. Always consult the Safety Data Sheet (SDS) before use.
How is (R)-N-Boc-2-phenylpyrrolidine typically packed and shipped?
+
We pack and ship (R)-N-Boc-2-phenylpyrrolidine according to international regulations for hazardous materials, including UN 2811, 6.1, PGIII. Our export services ensure compliance with all shipping requirements.
How can I request a quote or sample for (R)-N-Boc-2-phenylpyrrolidine?
+
To request a quote or sample, please use the 'Request a Quote' or 'Request a Sample' button on our website or contact our sales team directly with your inquiry, specifying the product CAS number 174311-02-5.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis