(R)-N-Fmoc-piperidine-2-carboxylic acid
(R)-N-Fmoc-piperidine-2-carboxylic acid (CAS: 101555-63-9) is a chiral building block with the molecular formula C21H21NO4 and a molecular weight of 351.40 g/mol. This compound, also known as Fmoc-D-pipecolic acid, is primarily utilised in asymmetric synthesis and peptide chemistry. Its protected piperidine structure makes it a valuable intermediate for creating complex chiral molecules, particularly in the development of novel pharmaceutical agents and chemical biology research.
- IUPAC
- Fmoc-D-pipecolic acid
Asymmetric Synthesis
Serves as a crucial chiral building block for the stereoselective synthesis of complex organic molecules. Its enantiomerically pure form facilitates the construction of specific stereocenters in target compounds.
Peptide Chemistry
Incorporated into peptide sequences as an unnatural amino acid derivative. This modification can alter the conformational properties, stability, and biological activity of peptides.
Pharmaceutical Intermediate
A key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its piperidine core is found in various therapeutic agents.
Chemical Biology
Used in the design and synthesis of probes and molecules for studying biological processes. Its unique structure allows for specific interactions with biological targets.
| Molecular weight | 351.40 |
|---|---|
| Empirical formula | C21H21NO4 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 154-158 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-N-Fmoc-piperidine-2-carboxylic acid used for?
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(R)-N-Fmoc-piperidine-2-carboxylic acid is used in asymmetric synthesis, peptide chemistry, as a pharmaceutical intermediate, and in chemical biology research. It acts as a chiral building block for creating complex stereocenters and modifying peptide structures.
What is the CAS number and formula for this compound?
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The CAS number is 101555-63-9, and the empirical formula is C21H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-N-Fmoc-piperidine-2-carboxylic acid with an assay of 97%. This product is typically considered for research and development purposes and is not supplied as USP, BP, or EP grade.
What are the safety and handling recommendations for this chemical?
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This compound is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is (R)-N-Fmoc-piperidine-2-carboxylic acid packed and shipped?
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The product is stored at 2-8°C. While specific packing details vary, TSS ensures that all chemicals are securely packed for export in compliance with international shipping regulations, including the classification as UN 3077, 9/PG 3.
How can I request a sample or a quote?
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To request a sample or a quote for (R)-N-Fmoc-piperidine-2-carboxylic acid, please contact the TSS sales team through our website or by phone. Please specify the quantity required and your delivery location.
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