6-Carboxytetramethylrhodamine
6-Carboxytetramethylrhodamine (CAS 91809-67-5) is a single isomer fluorophore with the empirical formula C25H22N2O5 and a molecular weight of 430.45 g/mol. It is highly suitable for fluorescence applications, emitting at λex 543 nm and λem 575 nm. This compound is primarily utilised as a labelling agent, particularly in automated DNA sequencing, and serves as a valuable tool in biochemical research and diagnostic detection methods.
- IUPAC
- 6-TAMRA
- Synonyms
- 6-TAMRA
Fluorescent Labelling
6-Carboxytetramethylrhodamine is a versatile fluorophore employed for labelling biomolecules. Its succinimidyl ester derivative is widely used in automated DNA sequencing, facilitating precise detection and analysis.
Biochemical Detection
As a fluorescent probe, this compound is instrumental in various biochemical detection assays. It can be used for staining proteins and nucleic acids, aiding in microscopy, flow cytometry, and immunoassays.
Research Reagent
This rhodamine derivative serves as a critical reagent in research laboratories. Its fluorescent properties make it suitable for developing novel detection systems and studying biological processes at a molecular level.
| Molecular weight | 430.45 |
|---|---|
| Empirical formula | C25H22N2O5 |
| Assay | ≥90% (HPLC) |
| Solubility | DMSO: solublemethanol: soluble |
| Application | The corresponding succinimidyl ester is a single isomer fluorophore most commonly used in automated DNA sequencing. |
| Suitability | suitable for fluorescence |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | single isomer |
|---|---|
| Product Line | BioReagent |
| Fluorescence | λex 543 nm; λem 575 nm in 0.1 M Tris pH 8.0 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Carboxytetramethylrhodamine used for?
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6-Carboxytetramethylrhodamine is used in fluorescent labelling, biochemical detection, and as a research reagent, notably in automated DNA sequencing and for staining proteins and nucleic acids.
What is the CAS number and formula for 6-Carboxytetramethylrhodamine?
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The CAS number for 6-Carboxytetramethylrhodamine is 91809-67-5, and its empirical formula is C25H22N2O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Carboxytetramethylrhodamine with an assay of ≥90% (HPLC). This product is intended for research use and is not represented as USP, BP, or EP grade.
What are the safety considerations for handling 6-Carboxytetramethylrhodamine?
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When handling, personal protective equipment including eyeshields and gloves is essential. In areas with potential for aerosol generation, a type N95 (US) or type P1 (EN143) respirator filter should be used. It carries a WGK Germany rating of 3.
How is 6-Carboxytetramethylrhodamine supplied and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 6-Carboxytetramethylrhodamine, which is carefully packaged and shipped according to international regulations for chemical substances.
How can I request a sample or quote for 6-Carboxytetramethylrhodamine?
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To request a sample or a quotation for 6-Carboxytetramethylrhodamine, please contact our sales department through the TSS website or by calling our office directly.
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