(R)-(−)-Glycidyl butyrate
(R)-(−)-Glycidyl butyrate, CAS 60456-26-0, with the molecular formula C7H12O3 and a molecular weight of 144.17, is a chiral epoxide. This compound serves as a valuable building block in asymmetric synthesis and general chemical manufacturing. Its specific stereochemistry makes it particularly useful for introducing chiral centres in complex organic molecules, contributing to the development of pharmaceuticals and other fine chemicals.
- IUPAC
- (R)-(−)-Oxirane-2-methanol butyrate
- Synonyms
- (R)-(−)-Oxirane-2-methanol butyrate
Asymmetric Synthesis
As a chiral building block, (R)-(−)-Glycidyl butyrate is instrumental in enantioselective synthesis. It allows for the stereocontrolled introduction of functional groups, crucial for the production of enantiopure compounds.
Pharmaceutical Intermediates
This epoxide derivative is employed in the synthesis of complex pharmaceutical intermediates. Its chiral nature is essential for creating active pharmaceutical ingredients (APIs) with specific biological activities.
Organic Synthesis Reagent
In general organic synthesis, (R)-(−)-Glycidyl butyrate acts as a versatile reagent for creating various functionalised molecules. It can be opened stereoselectively to yield chiral alcohols and other derivatives.
| Molecular weight | 144.17 |
|---|---|
| Empirical formula | C7H12O3 |
| Assay | 96% |
| Boiling point | 197 °C(lit.) |
| Density | 1.032 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.428(lit.) |
| Optical activity | [α]25/D −31°, neat |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 84 °C / 183.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-42/43 |
| Safety statements (S) | 23-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-Glycidyl butyrate used for?
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(R)-(−)-Glycidyl butyrate is primarily used as a chiral building block in asymmetric synthesis and for the preparation of pharmaceutical intermediates and other complex organic molecules.
What is the CAS number and formula for (R)-(−)-Glycidyl butyrate?
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The CAS number for (R)-(−)-Glycidyl butyrate is 60456-26-0, and its empirical formula is C7H12O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-Glycidyl butyrate with an assay of 96%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety hazards associated with (R)-(−)-Glycidyl butyrate?
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(R)-(−)-Glycidyl butyrate is classified with the signal word 'Danger' and carries hazard statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, is essential during handling.
How is (R)-(−)-Glycidyl butyrate packed, shipped, and exported?
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Tech Serve Solutions ensures appropriate packaging for (R)-(−)-Glycidyl butyrate in compliance with transport regulations. We are experienced global suppliers and exporters of fine chemicals.
How can I request a sample or quote for (R)-(−)-Glycidyl butyrate?
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To request a sample or a quotation for (R)-(−)-Glycidyl butyrate, please contact our sales team through the website or by phone, providing your specific requirements.
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