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(R)-(−)-Glycidyl methyl ether

CAS 64491-70-9C4H8O2Chemical Synthesis

(R)-(−)-Glycidyl methyl ether (CAS 64491-70-9), a chiral epoxide with the formula C4H8O2 and a molecular weight of 88.11 g/mol, is a valuable building block in asymmetric synthesis. Its chemical structure allows for stereoselective reactions, making it useful in the preparation of complex organic molecules. This compound serves as a key intermediate in the synthesis of pharmaceuticals and other fine chemicals where chirality is crucial.

IUPAC
(R)-(−)-2-(Methoxymethyl)oxirane,(R)-(−)-Methyl glycidyl ether
Synonyms
(R)-(−)-2-(Methoxymethyl)oxirane(R)-(−)-Methyl glycidyl ether
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(R)-(−)-Glycidyl methyl ether (C4H8O2) — chemical structure, CAS 64491-70-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksEpoxidesOrganic Building Blocks
01 /Applications

Chiral Building Block

Utilised as a stereochemically defined epoxide, it introduces chirality into target molecules. This is essential for synthesising enantiomerically pure compounds used in pharmaceuticals and agrochemicals.

Organic Synthesis Intermediate

Serves as a versatile intermediate in organic synthesis, participating in ring-opening reactions to form functionalised alcohols and ethers. It is particularly useful for creating complex molecular architectures.

Asymmetric Synthesis

Plays a critical role in asymmetric synthesis, enabling the controlled construction of chiral centres. Its defined stereochemistry is leveraged to achieve high enantioselectivity in various chemical transformations.

02 /Properties
Molecular weight88.11
Empirical formulaC4H8O2
Assay97%
Boiling point110-111 °C(lit.)
Density0.982 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.406(lit.)
Optical activity[α]20/D −15°, c = 5 in toluene
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point17 °C / 62.6 °F
Transport (UN / ADR)UN 3271 3 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xi
Risk statements (R)11-19-36/37/38
Safety statements (S)16-26
Supplemental hazardsMay form explosive peroxides.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
64491-70-9
MDL number
MFCD00273372
PubChem substance
24868954
Beilstein registry
102505
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(−)-Glycidyl methyl ether used for?

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(R)-(−)-Glycidyl methyl ether is primarily used as a chiral building block and intermediate in asymmetric synthesis for creating complex organic molecules, particularly in the pharmaceutical and fine chemical industries.

What is the CAS number and chemical formula for (R)-(−)-Glycidyl methyl ether?

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The CAS number is 64491-70-9 and the chemical formula is C4H8O2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(−)-Glycidyl methyl ether with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

What are the primary safety hazards associated with (R)-(−)-Glycidyl methyl ether?

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(R)-(−)-Glycidyl methyl ether is highly flammable (H225) and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It may also form explosive peroxides.

How is (R)-(−)-Glycidyl methyl ether packed, shipped, or exported?

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(R)-(−)-Glycidyl methyl ether is shipped according to international regulations for hazardous materials, identified as UN 3271, Hazard Class 3, Packing Group II.

How can I request a sample or quote for (R)-(−)-Glycidyl methyl ether?

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To request a sample or quote, please contact our sales department through the website or by phone, providing the product name and CAS number.

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