(R)-(−)-Epichlorohydrin
(R)-(−)-Epichlorohydrin (CAS: 51594-55-9, C3H5ClO) is a chiral epoxide supplied by Tech Serve Solutions. With a molecular weight of 92.52 g/mol, this compound serves as a critical building block in asymmetric synthesis. Its primary documented application is in the preparation of a key intermediate for a stable Prostacyclin analogue (UT-15). TSS provides this high-purity chemical for research and development purposes.
- IUPAC
- (R)-(−)-2-(Chloromethyl)oxirane
- Synonyms
- (R)-(−)-2-(Chloromethyl)oxirane
Chiral Building Block
Serves as a fundamental chiral synthon in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules.
Pharmaceutical Intermediate Synthesis
Utilised in the synthesis of advanced pharmaceutical intermediates, notably for stable Prostacyclin (PGI2) analogues such as UT-15.
Organic Synthesis
A versatile reagent in general organic synthesis, allowing for the introduction of epoxide and chloromethyl functionalities into target molecules.
| Molecular weight | 92.52 |
|---|---|
| Empirical formula | C3H5ClO |
| Assay | ≥98.5% (sum of enantiomers, GC) |
| Boiling point | 114 °C(lit.) |
| Density | 1.180 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.438(lit.)n20/D 1.438 |
| Optical activity | [α]20/D −44.5±1°, neat |
| Vapour pressure | 10 mmHg (16.6 °C) |
| Vapour density | 3.29 (vs air) |
| Autoignition temp | 772 °F |
| Storage temperature | 2-8°C |
| Application | Building block for the synthesis of a key intermediate in the synthesis of stable PGI2 analogue UT-15.1 |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H331Toxic if inhaled
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 32 °C / 89.6 °F |
| Transport (UN / ADR) | UN 2023 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-10-23/24/25-34-43 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-Epichlorohydrin used for?
+
(R)-(−)-Epichlorohydrin is primarily used as a chiral building block in asymmetric synthesis and for the preparation of key intermediates in pharmaceutical synthesis, such as those for stable Prostacyclin analogues.
What are the CAS number and formula for (R)-(−)-Epichlorohydrin?
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The CAS number is 51594-55-9 and the molecular formula is C3H5ClO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-Epichlorohydrin with an assay of ≥98.5% (sum of enantiomers, GC). TSS does not represent this product as USP, BP, or EP grade.
How should (R)-(−)-Epichlorohydrin be handled safely?
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(R)-(−)-Epichlorohydrin is a dangerous substance. It is flammable (flash point 32 °C), toxic if swallowed, in contact with skin, or if inhaled, and causes severe skin burns and eye damage. It may also cause an allergic skin reaction and is suspected of causing cancer. Always use appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, and handle only in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is (R)-(−)-Epichlorohydrin packed and shipped?
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(R)-(−)-Epichlorohydrin is packed and shipped according to international regulations for hazardous materials, suitable for global export by Tech Serve Solutions.
How can I request a sample or quote for (R)-(−)-Epichlorohydrin?
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To request a sample or a quotation for (R)-(−)-Epichlorohydrin, please contact the Tech Serve Solutions sales team via our website or by phone.
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