(R)-(−)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone

CAS 52813-63-5C5H8O3Chemical Synthesis

(R)-(−)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone (CAS: 52813-63-5) is a chiral building block with the molecular formula C5H8O3 and a molecular weight of 116.12. This versatile synthon plays a crucial role in asymmetric synthesis, facilitating the creation of complex natural and unnatural products. It is supplied by Tech Serve Solutions with a minimum purity of 97%, making it suitable for various research and synthetic applications.

IUPAC: (R)-γ-Hydroxymethyl-γ-butyrolactone,(R)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone,(R)-5-Hydroxymethyl-2-oxotetrahydrofuran
Synonyms: (R)-γ-Hydroxymethyl-γ-butyrolactone(R)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone(R)-5-Hydroxymethyl-2-oxotetrahydrofuran

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(R)-(−)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone (C5H8O3) — chemical structure, CAS 52813-63-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksFuransHeterocyclic Building Blocks

01 /Applications

Asymmetric Synthesis

This compound serves as a valuable chiral synthon in asymmetric synthesis, enabling the stereoselective construction of target molecules. Its defined stereochemistry is critical for building complex molecular architectures.

Synthesis of Natural Products

It is employed in the synthesis of various natural products, where its chiral framework is incorporated into the final structure. This application leverages its utility in complex organic synthesis.

Chiral Building Block

As a chiral building block, it provides a readily available source of chirality for synthetic chemists. It is useful for introducing specific stereocentres into molecules.

02 /Properties

Molecular weight	116.12
Empirical formula	C5H8O3
Assay	97%
Boiling point	101-102 °C/0.048 mmHg(lit.)
Density	1.237 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.47(lit.)
Optical activity	[α]20/D −56°, c = 3 in chloroform
Storage temperature	2-8°C
Application	Versatile chiral synthon used in the synthesis of natural and unnatural products.1,2,3

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Flash point	110 °C / 230 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

52813-63-5

MDL number

MFCD00040528

PubChem substance

24861173

Beilstein registry

1680285

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(−)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone used for?

(R)-(−)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a versatile chiral synthon used in the synthesis of natural and unnatural products. It functions as a key building block in asymmetric synthesis.

What are the CAS number and formula for this chemical?

The CAS number is 52813-63-5, and the empirical formula is C5H8O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (R)-(−)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone with an assay of 97%. This product is not supplied as USP, BP, or EP grade and is intended for research and laboratory use.

What are the safety and handling considerations for this compound?

This compound is classified under WGK 2 and has a flash point of 110 °C (230 °F). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Refer to the Safety Data Sheet for comprehensive handling information.

How is this chemical shipped or exported?

Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of handling national and international shipments.

How can I request a sample or quote?

To request a sample or a quotation for (R)-(−)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone, please contact our sales team through the website or by phone.