(R)-(−)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
(R)-(−)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate (CAS 23788-74-1) is a chiral building block with a molecular weight of 286.34 g/mol. This tosylate ester is valuable in organic synthesis, particularly for asymmetric reactions. It serves as a protected alcohol derivative, facilitating stereoselective transformations in the synthesis of complex organic molecules. Available from Tech Serve Solutions with a 97% assay, it is supplied for research and chemical synthesis applications.
- IUPAC
- (R)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate,1,2-Isopropylidene-sn-glycerol 3-tosylate,D-α,β-Isopropylideneglycerol γ-tosylate
- Synonyms
- 23788-74-1C13H18O5S(R)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate1,2-Isopropylidene-sn-glycerol 3-tosylateD-α,β-Isopropylideneglycerol γ-tosylate
Chiral Building Block in Asymmetric Synthesis
This compound is a key intermediate for introducing chirality in organic molecules. Its well-defined stereochemistry is exploited in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals.
Protected Alcohol Precursor
The dioxolane group acts as a protecting group for a diol, allowing selective reactions at the tosylate moiety. This enables controlled synthetic strategies in multi-step syntheses.
Organic Synthesis Intermediate
Its tosylate functionality is an excellent leaving group, making it reactive towards nucleophilic substitution. This property is leveraged in the construction of carbon-carbon and carbon-heteroatom bonds.
| Molecular weight | 286.34 |
|---|---|
| Empirical formula | C13H18O5S |
| Assay | 97% |
| Density | 1.208 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.506(lit.) |
| Optical activity | [α]20/D −7.0°, neat |
| Storage temperature | −20°C |
| Melting point | 41-43 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate used for?
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(R)-(−)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate is primarily used as a chiral building block in asymmetric synthesis and as a protected alcohol precursor in organic synthesis.
What is the CAS number and formula for this compound?
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The CAS number is 23788-74-1, and the empirical formula is C13H18O5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is supplied for research and technical use and is not guaranteed to be of USP, BP, or EP grade.
How should (R)-(−)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate be handled safely?
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This compound is a warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation. Store at −20°C.
Is this chemical a controlled substance?
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Based on the provided data, this chemical is not listed as a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packages and exports chemicals according to international shipping regulations and customer requirements, ensuring safe transit.
How can I request a sample or quote?
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To request a sample or quote for (R)-(−)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate, please contact the Tech Serve Solutions sales team via our website or by phone.
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