(R)-(−)-2-(2,5-Dihydrophenyl)glycine
(R)-(−)-2-(2,5-Dihydrophenyl)glycine (CAS: 26774-88-9) is a chiral unnatural amino acid derivative with the molecular formula C8H11NO2 and a molecular weight of 153.18 g/mol. It finds utility as a building block in chemical synthesis, particularly within the fields of chemical biology and peptide chemistry. Its specific stereochemistry makes it valuable for creating complex molecular architectures.
- IUPAC
- (R)-α-Amino-1,4-cyclohexadiene-1-acetic acid
- Synonyms
- (R)-α-Amino-1,4-cyclohexadiene-1-acetic acidC8H11NO2

Chemical Synthesis Building Block
This compound serves as a chiral intermediate in the synthesis of complex organic molecules. Its unique structure allows for the introduction of specific stereocenters in target compounds.
Peptide Chemistry
As an unnatural amino acid derivative, it can be incorporated into peptide sequences to modify their properties, such as stability or biological activity. This is crucial for developing novel peptidomimetics.
Chemical Biology Research
It is utilized in research settings to explore new chemical entities and probe biological pathways. Its unnatural origin can offer advantages in studying protein-ligand interactions or developing new diagnostic tools.
| Molecular weight | 153.18 |
|---|---|
| Empirical formula | C8H11NO2 |
| Assay | 98% |
| Optical activity | [α]20/D −154°, c = 1 in H2O |
| Melting point | 280 °C (dec.)(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-(2,5-Dihydrophenyl)glycine used for?
+
(R)-(−)-2-(2,5-Dihydrophenyl)glycine is primarily used as a building block in chemical synthesis, peptide chemistry, and chemical biology research due to its chiral nature and structure as an unnatural amino acid derivative.
What is the CAS number and chemical formula for (R)-(−)-2-(2,5-Dihydrophenyl)glycine?
+
The CAS number is 26774-88-9 and the empirical formula is C8H11NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(−)-2-(2,5-Dihydrophenyl)glycine with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and chemical synthesis applications.
How should (R)-(−)-2-(2,5-Dihydrophenyl)glycine be handled safely?
+
As per its WGK Germany rating of 3, (R)-(−)-2-(2,5-Dihydrophenyl)glycine is considered to be hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling procedures.
Can Tech Serve Solutions export (R)-(−)-2-(2,5-Dihydrophenyl)glycine?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and can export (R)-(−)-2-(2,5-Dihydrophenyl)glycine worldwide.
How can I request a quote or sample for (R)-(−)-2-(2,5-Dihydrophenyl)glycine?
+
To request a quote or sample, please contact our sales department via the website or direct email, providing your contact details and the product information (CAS: 26774-88-9).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis