(R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol
(R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol (CAS: 14347-78-5) is a chiral building block with the molecular formula C6H12O3 and a molecular weight of 132.16 g/mol. This optically active compound, with an optical purity of ≥99% ee, serves as a valuable synthon in asymmetric synthesis. It is primarily utilized in the preparation of complex organic molecules, including specialized ethers and phosphates, contributing to advancements in chemical synthesis and research.
- IUPAC
- 2,3-Isopropylidene-sn-glycerol,L-α,β-Isopropylideneglycerol,L-2,3-O-isopropylidene-sn-glycerol
- Synonyms
- 14347-78-5C6H12O32,3-Isopropylidene-sn-glycerolL-α,β-IsopropylideneglycerolL-2,3-O-isopropylidene-sn-glycerol
Chiral Synthon in Organic Synthesis
This compound is employed as a chiral building block for the stereoselective synthesis of various complex organic molecules. Its specific stereochemistry is crucial for constructing target molecules with defined spatial arrangements.
Preparation of Tetraoxaspiroundecanes
Both enantiomers of 2,2-Dimethyl-1,3-dioxolane-4-methanol are recognised synthons in the preparation of tetraoxaspiroundecanes. This application highlights its utility in creating specific cyclic ether structures.
Synthesis of Diglycerides and Glycerol Derivatives
The compound is instrumental in synthesising diglycerides and glyceryl phosphates. This role is vital in areas requiring modified glycerol backbones for specialised applications.
| Molecular weight | 132.16 |
|---|---|
| Empirical formula | C6H12O3 |
| Assay | 98% |
| Boiling point | 72-73 °C/8 mmHg(lit.) |
| Density | 1.062 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.434(lit.) |
| Optical activity | [α]20/D −13.7°, neat |
| Optical purity | ee: 99% (GLC) |
| Storage temperature | 2-8°C |
| Application | Both (R)- and (S)-forms are chiral synthons used in the preparation of tetraoxaspiroundecanes,1 diglycerides,2 and glyceryl phosphates.3 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol used for?
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(R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol is used as a chiral synthon in organic synthesis, particularly for preparing tetraoxaspiroundecanes, diglycerides, and glyceryl phosphates.
What are the CAS number and formula for this chemical?
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The CAS number is 14347-78-5, and the molecular formula is C6H12O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol with an assay of 98% and an optical purity of ≥99% ee (GLC). We do not represent this product as USP, BP, or EP grade.
How should (R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. It should be stored at 2-8°C to maintain its integrity. The flash point is 79°C (174.2°F).
Is (R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol a controlled substance?
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The provided data does not indicate that (R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol is a controlled substance.
How can I request a sample or a quote?
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Please contact our sales team via the website or by phone to request a sample or a quotation for (R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals like (R)-(−)-2,2-Dimethyl-1,3-dioxolane-4-methanol.
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