(R)-(−)-1-Phenyl-1,2-ethanediol
(R)-(−)-1-Phenyl-1,2-ethanediol (CAS: 16355-00-3) is a chiral diol with the linear formula HOCH₂CH(C₆H₅)OH and a molecular weight of 138.16 g/mol. It is a valuable building block in organic synthesis, particularly for asymmetric reactions. Available in high purity, it serves as a key intermediate in the synthesis of complex molecules within the pharmaceutical and fine chemical industries. Its defined stereochemistry makes it crucial for creating enantiomerically pure target compounds.
- IUPAC
- (−)-Styrene glycol,(R)-(−)-Phenylethylene glycol
- Synonyms
- (−)-Styrene glycol(R)-(−)-Phenylethylene glycol(R)-1-Phenyl-1,2-ethanediol
Asymmetric Synthesis
Serves as a chiral auxiliary or precursor in stereoselective transformations. Its defined (R)-configuration enables the synthesis of enantiomerically enriched products.
Pharmaceutical Intermediates
A key building block for the synthesis of various active pharmaceutical ingredients (APIs). Its chiral nature is essential for developing drugs with specific biological activities.
Organic Building Block
Utilised in diverse organic synthesis pathways for constructing complex molecular architectures. Its diol functionality allows for various derivatizations and reactions.
Chiral Pool Synthesis
Incorporated into synthesis strategies that leverage readily available chiral molecules to introduce stereocentres into target compounds.
| Molecular weight | 138.16 |
|---|---|
| Linear formula | HOCH2CH(C6H5)OH |
| Assay | 99% |
| Boiling point | 272-274 °C(lit.) |
| Optical activity | [α]20/D −69°, c = 1 in chloroform |
| Melting point | 64-67 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-1-Phenyl-1,2-ethanediol used for?
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(R)-(−)-1-Phenyl-1,2-ethanediol is primarily used in asymmetric synthesis as a chiral building block for creating enantiomerically pure pharmaceutical intermediates and complex organic molecules.
What is the CAS number and formula for (R)-(−)-1-Phenyl-1,2-ethanediol?
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The CAS number is 16355-00-3 and the linear formula is HOCH₂CH(C₆H₅)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-1-Phenyl-1,2-ethanediol with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(−)-1-Phenyl-1,2-ethanediol be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a type N95 (US) or type P1 (EN143) respirator filter if necessary, as this compound is classified under WGK 3 in Germany.
How is (R)-(−)-1-Phenyl-1,2-ethanediol packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant transport and customs regulations. Specific packaging details are available upon request.
How can I request a sample or quote?
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To request a sample or a quote for (R)-(−)-1-Phenyl-1,2-ethanediol, please contact our sales team via the website or direct email, providing your specific requirements.
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