Tetraethyl pyrophosphite
Tetraethyl pyrophosphite (CAS 21646-99-1) is an organic phosphorus compound used in chemical synthesis. Its molecular formula is (C2H5O)2POP(OC2H5)2 and it has a molecular weight of 258.19. This chemical serves as a valuable building block in organic chemistry, particularly in the synthesis of other organophosphorus compounds. It is supplied by Tech Serve Solutions with an assay of 96%.

Preparation of Diethyl Fluorophosphonites
Tetraethyl pyrophosphite has been utilized as a precursor in the synthesis of diethyl fluorophosphonites, highlighting its role in the preparation of specialized organofluorine and organophosphorus compounds.
Organic Synthesis Building Block
As an organic building block, this compound is instrumental in constructing more complex molecular architectures within organic chemistry research and development.
Phosphorus Chemistry
It falls under the category of organic phosphates/phosphites and phosphorus compounds, indicating its utility in reactions involving phosphorus functional groups.
| Molecular weight | 258.19 |
|---|---|
| Linear formula | (C2H5O)2POP(OC2H5)2 |
| Assay | 96% |
| Boiling point | 79-81 °C/1 mmHg(lit.) |
| Density | 1.057 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.434(lit.) |
| Application | Tetraethyl pyrophosphite was used in the preparation of diethyl fluorophosphonites1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetraethyl pyrophosphite used for?
+
Tetraethyl pyrophosphite is primarily used as a building block in chemical synthesis, notably in the preparation of diethyl fluorophosphonites.
What is the CAS number and formula for Tetraethyl pyrophosphite?
+
The CAS number for Tetraethyl pyrophosphite is 21646-99-1, and its linear formula is (C2H5O)2POP(OC2H5)2.
What is the purity of Tetraethyl pyrophosphite offered by TSS?
+
Tech Serve Solutions supplies Tetraethyl pyrophosphite with a minimum assay of 96%.
What are the main hazards associated with Tetraethyl pyrophosphite?
+
Tetraethyl pyrophosphite is classified with GHS07 symbol and a warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be used.
How is Tetraethyl pyrophosphite supplied and exported?
+
As a global supplier and exporter, Tech Serve Solutions provides Tetraethyl pyrophosphite packaged and shipped according to international regulations for chemical substances.
How can I request a quote for Tetraethyl pyrophosphite?
+
To request a quote, please contact the Tech Serve Solutions sales team with your specific requirements.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis