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Tetraethyl methylenediphosphonate

CAS 1660-94-2CH2[P(O)(OCH2CH3)2]2Chemical Synthesis

Tetraethyl methylenediphosphonate (CAS 1660-94-2), molecular formula CH2[P(O)(OCH2CH3)2]2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

IUPAC
Bis(diethoxyphosphinyl)methane,Methylenediphosphonic acid tetraethylester,NSC 133889
Tetraethyl methylenediphosphonate
C-C Bond FormationChemical SynthesisOlefinationSynthetic Reagents
01 /Properties
Molecular weight288.21
Linear formulaCH2[P(O)(OCH2CH3)2]2
Assay97%
Boiling point171-174 °C/11 mmHg(lit.)
Density1.16 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.442(lit.)
ApplicationReactant for synthesis of: • Dual substrate-site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase1• Unnatural alpha-amino acid derivatives containing gem-biphosphonates2• Biphenyl sulfonylamino Me bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption3• Lycopene via Wittig-Horner reaction4• Alkylaminoethylbisphosphinic acids to target farnesyl diphosphate synthase5• Aromatic bisphosphonates for use as inhibitors of geranylgeranyl diphosphate synthase6Precursor for synthesis of dendritic polyglycerol anions used toward L-selectin inhibition7
02 /Safety & handling
Harmful / irritant
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point110 °C / 230 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
1660-94-2
MDL number
MFCD00039887
Beilstein registry
1813241
04 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Tetraethyl methylenediphosphonate?

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Tetraethyl methylenediphosphonate (CAS 1660-94-2), molecular formula CH2[P(O)(OCH2CH3)2]2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.

What grades of Tetraethyl methylenediphosphonate does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Tetraethyl methylenediphosphonate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of Tetraethyl methylenediphosphonate?

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Tetraethyl methylenediphosphonate has CAS number 1660-94-2 and molecular formula CH2[P(O)(OCH2CH3)2]2. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for Tetraethyl methylenediphosphonate?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of Tetraethyl methylenediphosphonate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should Tetraethyl methylenediphosphonate be stored?

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Store Tetraethyl methylenediphosphonate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is Tetraethyl methylenediphosphonate used for?

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Tetraethyl methylenediphosphonate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for Tetraethyl methylenediphosphonate?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need Tetraethyl methylenediphosphonate in a specific grade or volume?

Request a quote