Propionyl bromide
Propionyl bromide (CAS: 598-22-1), with the linear formula CH3CH2COBr and a molecular weight of 136.98 g/mol, is a reactive acyl halide. It functions as a key building block in organic synthesis, particularly in the introduction of the propionyl group. It is commonly employed in the chemical industry for the production of various organic compounds and intermediates. This compound is supplied by TSS with an assay of 97%.

Organic Synthesis Reagent
Propionyl bromide serves as a valuable acylating agent in organic chemistry. It is used to introduce the propionyl group (CH3CH2CO-) into various organic molecules, facilitating the synthesis of esters, amides, and other derivatives.
Pharmaceutical Intermediate Production
This compound finds application in the multi-step synthesis of pharmaceutical intermediates. Its reactivity allows for the efficient formation of carbon-carbon and carbon-heteroatom bonds crucial in drug discovery and development.
Research and Development
As a versatile building block, propionyl bromide is utilised in academic and industrial research laboratories for exploring novel synthetic routes and developing new chemical entities.
| Molecular weight | 136.98 |
|---|---|
| Linear formula | CH3CH2COBr |
| Assay | 97% |
| Boiling point | 103-104 °C(lit.) |
| Density | 1.521 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.455(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 52 °C / 125.6 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Propionyl bromide used for?
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Propionyl bromide (CAS: 598-22-1) is primarily used as an acylating agent in organic synthesis for introducing the propionyl group, a building block for producing esters, amides, and other organic compounds, including pharmaceutical intermediates.
What is the CAS number and formula for Propionyl bromide?
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The CAS number for Propionyl bromide is 598-22-1 and its linear formula is CH3CH2COBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Propionyl bromide with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should Propionyl bromide be handled safely?
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Propionyl bromide is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). It reacts violently with water. Handle with extreme caution, using appropriate personal protective equipment including a faceshield, full-face respirator, gloves, and goggles. Ensure adequate ventilation and avoid contact with water. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is Propionyl bromide packed and shipped by TSS globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Propionyl bromide, adhering to all relevant shipping regulations.
How can I request a quote or sample for Propionyl bromide?
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To request a quote or sample for Propionyl bromide, please contact our sales department through the website or by phone, providing your specific requirements.
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