Propionitrile
Propionitrile (CAS: 107-12-0), with the chemical formula CH3CH2CN and a molar mass of 55.08 g/mol, is a colourless liquid organic compound. It is a valuable building block in chemical synthesis, notably used in the creation of triazine derivatives and in spectroscopic studies. Propionitrile is also a key intermediate in the production of various organic compounds. Tech Serve Solutions supplies this versatile nitrile for research and industrial applications.
- IUPAC
- Ethyl cyanide
- Synonyms
- Ethyl cyanide

Synthesis of Triazine Derivatives
Propionitrile serves as a reactant in the cyclotrimerisation of nitriles, leading to the formation of triazine derivatives. This application is facilitated by catalysts such as mesoporous graphitic C3N4.
Spectroscopic Research
This compound is utilised in spectroscopic studies, such as Raman spectroscopy, to investigate complex formation. An example includes its use in studying the interaction between o-cresol and propionitrile.
Organic Synthesis Intermediate
As a C3 nitrile, propionitrile functions as a fundamental building block in organic synthesis. It is employed in the construction of more complex molecules and organic frameworks.
| Molecular weight | 55.08 |
|---|---|
| Linear formula | CH3CH2CN |
| Assay | 99% |
| Boiling point | 97 °C(lit.) |
| Density | 0.772 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.366(lit.) |
| Solubility | water: soluble11.9g/100g at 40 °Cwater: soluble29g/100g at 100 °CDMF: misciblealcohol: misciblediethyl ether: miscible |
| Melting point | −93 °C(lit.) |
| Application | Propionitrile was used in mesoporous graphitic C3N4 catalyzed cyclotrimerisation of various nitriles into triazine derivatives1. It was used in Raman spectroscopic study of complex formation between o-cresol and propionitrile2. |


Hazard statements
- H225Highly flammable liquid and vapour
- H300Fatal if swallowed
- H319Causes serious eye irritation
- H332Harmful if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P302IF ON SKIN
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 6 °C / 42.8 °F |
| Transport (UN / ADR) | UN 2404 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T+ |
| Risk statements (R) | 11-20-25-27-36 |
| Safety statements (S) | 9-16-28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Propionitrile used for?
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Propionitrile is used as a building block in chemical synthesis, including the formation of triazine derivatives, and in spectroscopic studies. It acts as an intermediate in the production of various organic compounds.
What is the CAS number and chemical formula for Propionitrile?
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The CAS number for Propionitrile is 107-12-0, and its chemical formula is CH3CH2CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Propionitrile with a minimum assay of 99%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should Propionitrile be handled safely?
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Propionitrile is a highly flammable liquid and vapour (H225) and is toxic if swallowed or in contact with skin (H300 + H310). It is also harmful if inhaled (H332) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, away from ignition sources. Always consult the Safety Data Sheet (SDS) before use.
How is Propionitrile packed and shipped?
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Propionitrile is carefully packed in compliance with all relevant transportation regulations. TSS exports fine chemicals globally, ensuring secure and appropriate packaging for international shipment.
How can I request a quote or sample of Propionitrile?
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To request a quote or sample of Propionitrile, please contact our sales team through the website or by calling our dedicated order line. Our team will be pleased to assist you.
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