Phenserine
Phenserine (CAS: 101246-66-6), with the molecular formula C20H23N3O2 and a molecular weight of 337.42 g/mol, is a bioactive small molecule primarily recognised for its role as a cholinesterase inhibitor. Supplied as an off-white solid, Phenserine is employed in biochemical research, particularly within neuroscience and cell signaling studies. Its ability to inhibit cholinesterase makes it a valuable tool for investigating cholinergic neurotransmission and related biological pathways.
- IUPAC
- (−)-N-Phenylcarbamoyleseroline,1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethyl-pyrrolo[2,3-b]indol-5-ol phenylcarbamate (ester)

Neuroscience Research
Phenserine serves as a crucial tool in neuroscience for investigating the mechanisms of cholinergic neurotransmission and the function of cholinesterase enzymes. Its inhibitory properties aid in understanding neurological disorders where acetylcholine signalling is implicated.
Biochemical Assays
As a cholinesterase inhibitor, Phenserine is utilised in biochemical assays to study enzyme kinetics and inhibition profiles. This application is vital for developing and validating new therapeutic agents targeting the cholinergic system.
Cell Biology Studies
This compound finds application in cell biology research to modulate cholinergic signalling pathways within cellular models. Researchers use Phenserine to explore cellular responses to changes in acetylcholine levels and its enzymatic breakdown.
| Molecular weight | 337.42 |
|---|---|
| Empirical formula | C20H23N3O2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | off-white |
| Solubility | H2O: DMSO: >5 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenserine used for?
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Phenserine is primarily used in neuroscience and biochemical research as a cholinesterase inhibitor to study cholinergic neurotransmission, enzyme kinetics, and cellular signalling pathways.
What is the CAS number and formula for Phenserine?
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The CAS number for Phenserine is 101246-66-6, and its molecular formula is C20H23N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenserine with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Phenserine be handled and stored?
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Phenserine is an irritant to the skin, eyes, and respiratory system (H315-H319-H335). It should be handled with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Store at 2-8°C.
How is Phenserine packed and shipped?
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Phenserine is typically supplied as an off-white solid. TSS offers global export services, ensuring proper packaging and documentation for international shipments.
How can I request a quote or sample for Phenserine?
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To request a quote or a sample of Phenserine, please contact our sales team through the website or by phone, providing your specific requirements.
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