PF-477736
PF-477736 (CAS: 952021-60-2) is a chemical compound with the molecular formula C22H25N7O2 and a molecular weight of 419.48 g/mol. This yellow powder is recognised for its role as a bioactive small molecule. Its primary applications are within cell biology research, focusing on cell signaling, kinase/phosphatase biology, and the study of checkpoint kinases, particularly in the context of neuroscience.
- IUPAC
- (2R)-2-Amino-2-cyclohexyl-N-[2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-5,6-dihydro-1H-[1,2]diazepino[4,5,6-cd]indol-8-yl]-acetamide,PF-00477736

Cell Biology Research
PF-477736 serves as a valuable tool in cell biology research. It is utilized to investigate cellular pathways, particularly those involving cell signaling and kinase activities.
Kinase/Phosphatase Inhibition Studies
This compound is employed in studies focused on serine/threonine kinase inhibitors and checkpoint kinase (ChK) pathways. It aids in understanding the regulation of these critical cellular processes.
Neuroscience Research
Within neuroscience, PF-477736 is used to explore cell signaling mechanisms and their implications. Its application contributes to the understanding of neuronal function and related biological processes.
| Molecular weight | 419.48 |
|---|---|
| Empirical formula | C22H25N7O2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Solubility | DMSO: ≥20 mg/mL |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PF-477736 used for?
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PF-477736 is primarily used in cell biology research, focusing on cell signaling, kinase/phosphatase biology, and the study of checkpoint kinases (ChK), particularly in neuroscience research. It is a bioactive small molecule.
What are the CAS number and formula for PF-477736?
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The CAS number for PF-477736 is 952021-60-2, and its empirical formula is C22H25N7O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PF-477736 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for PF-477736?
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PF-477736 is classified with a WGK Germany rating of 3, indicating it is hazardous to water. Standard laboratory precautions should be observed when handling, including appropriate personal protective equipment and working in a well-ventilated area.
How is PF-477736 typically packed, shipped, and exported?
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PF-477736 is typically supplied as a yellow powder. It is stored at 2-8°C. TSS can manage global export of this chemical.
How can I request a sample or quote for PF-477736?
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To request a sample or quote for PF-477736, please contact our sales department through the website or by phone.
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