PF-4708671

CAS 1255517-76-0C19H21F3N6Cell Biology

PF-4708671 (CAS: 1255517-76-0), a fluorinated benzimidazole derivative with the molecular formula C19H21F3N6 and a molecular weight of 390.41 g/mol, is supplied as an off-white powder. This compound is recognised for its role in biochemical research, particularly as a selective inhibitor of p70 S6 kinase. Its utility extends to cell biology and signalling studies, offering a valuable tool for investigating cell growth and proliferation pathways.

IUPAC: 2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole

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PF-4708671 (C19H21F3N6) — chemical structure, CAS 1255517-76-0; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyKinase/Phosphatase BiologyPfizer CompoundsProtein Kinases (PK)

01 /Applications

p70 S6 Kinase Inhibition

PF-4708671 is a potent and selective inhibitor of p70 S6 kinase (S6K1), a key enzyme in the PI3K/Akt/mTOR pathway. It is widely used in research to study the roles of S6K1 in cell growth, proliferation, and protein synthesis.

Cell Biology Research

This compound serves as a valuable tool in cell biology for investigating cellular processes regulated by S6K1. It aids in understanding signal transduction pathways relevant to cancer and other diseases.

Neuroscience Studies

Due to its involvement in cell signalling pathways, PF-4708671 may find applications in neuroscience research to explore the role of S6K1 in neuronal function and development.

02 /Properties

Molecular weight	390.41
Empirical formula	C19H21F3N6
Assay	≥98% (HPLC)
Form	powder
Colour	off-white
Solubility	DMSO: ≥20 mg/mL
Storage temperature	room temp

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1255517-76-0

05 /Additional specifications

Gene Information	human ... RPS6KB1(6198)mouse ... Rps6kb1(72508)rat ... Rps6kb1(83840)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is PF-4708671 used for?

PF-4708671 is primarily used as a research tool, particularly as a selective inhibitor of p70 S6 kinase, for studies in cell biology, cell signalling, and neuroscience.

What is the CAS number and formula for PF-4708671?

The CAS number for PF-4708671 is 1255517-76-0, and its molecular formula is C19H21F3N6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies PF-4708671 with a purity of ≥98% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.

How should PF-4708671 be handled safely?

PF-4708671 is classified as Danger with hazard statement H301 (Toxic if swallowed). Handle with extreme caution, using appropriate personal protective equipment and engineering controls to avoid ingestion. Consult the Safety Data Sheet for detailed handling instructions.

How is PF-4708671 packed, shipped, and exported?

PF-4708671 is typically supplied in standard laboratory packaging suitable for research chemicals. TSS is a global supplier and exporter, adhering to all relevant shipping and customs regulations for hazardous materials (UN 2811, Class 6.1).

How can I request a sample or quote for PF-4708671?

To request a sample or a quotation for PF-4708671, please contact our sales department through the website or by telephone, providing your research requirements and shipping details.