PF-431396 hydrate
PF-431396 hydrate (CAS 717906-29-1) is a chemical compound with the formula C22H21F3N6O3S · xH2O and a molecular weight of 506.50 (anhydrous basis). This off-white to blue-gray powder is primarily recognised for its role in biological research, particularly in cell signaling and neuroscience. It is used as a research tool for investigating pathways involving focal adhesion kinase (FAK) and other tyrosine kinases.
- IUPAC
- N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methyl-Methanesulfonamide hydrate
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Focal Adhesion Kinase (FAK) Research
PF-431396 hydrate serves as a valuable tool for researchers studying the role of Focal Adhesion Kinase (FAK) in cellular processes. Its inhibitory properties allow for the investigation of FAK's involvement in cell adhesion, migration, and survival.
Cell Signaling Studies
This compound is utilised in studies of cell signaling pathways, particularly those involving non-receptor tyrosine kinases. It helps elucidate complex signalling cascades relevant to cell biology and disease mechanisms.
Neuroscience Research
PF-431396 hydrate finds application in neuroscience research, contributing to the understanding of cellular mechanisms within the nervous system. Its specific targets make it relevant for exploring neurobiological functions.
| Molecular weight | 506.50 (anhydrous basis) |
|---|---|
| Empirical formula | C22H21F3N6O3S · xH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white to blue-gray |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PF-431396 hydrate used for?
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PF-431396 hydrate is used in research for studying focal adhesion kinase (FAK), cell signaling, and neuroscience. It acts as an inhibitor for certain tyrosine kinases.
What are the CAS number and formula for PF-431396 hydrate?
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The CAS number for the anhydrous form is 717906-29-1. The empirical formula for PF-431396 hydrate is C22H21F3N6O3S · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PF-431396 hydrate with a purity of ≥98% (HPLC). This product is intended for research use and is not supplied as USP, BP, or EP grade.
How should PF-431396 hydrate be handled safely?
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PF-431396 hydrate is classified as Danger (GHS06) and is toxic if swallowed (H301) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment in a well-ventilated area, following P301 + P310 and P305 + P351 + P338 precautionary statements.
How is PF-431396 hydrate packed, shipped, and exported?
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PF-431396 hydrate is typically supplied as an off-white to blue-gray powder and stored at 2-8°C. As a hazardous material (UN 2811 6.1 / PGIII), it is packed, shipped, and exported according to strict international regulations for dangerous goods.
How can I request a sample or quote for PF-431396 hydrate?
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To request a sample or quote for PF-431396 hydrate, please contact our sales team via the website or designated email address, providing your specific requirements.
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