PF-573228

CAS 869288-64-2C22H20F3N5O3SCell Biology

PF-573228 (CAS: 869288-64-2), a fluorinated organic compound with the molecular formula C22H20F3N5O3S and a molecular weight of 491.49 g/mol, is supplied as a white to off-white powder. It functions as a potent inhibitor, particularly targeting Focal Adhesion Kinase (FAK). This molecule is a valuable tool in cell biology research, aiding studies into cell signaling, neuroscience, and kinase/phosphatase pathways. Its primary application lies in preclinical research settings for investigating cellular processes.

IUPAC: 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one,PF-228
Synonyms: 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one,PF-228

Email us

PF-573228 (C22H20F3N5O3S) — chemical structure, CAS 869288-64-2; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyFocal Adhesion Kinase (FAK)Kinase/Phosphatase BiologyPfizer Compounds More...

01 /Applications

Focal Adhesion Kinase (FAK) Inhibition

PF-573228 acts as a selective inhibitor of Focal Adhesion Kinase (FAK), a non-receptor tyrosine kinase critical for cell adhesion, migration, and survival. Its use is instrumental in dissecting FAK-mediated signalling pathways in various cellular contexts.

Cell Biology Research

This compound is employed in cell biology studies to investigate cellular processes influenced by FAK activity, including cell proliferation, differentiation, and response to extracellular matrix interactions. It aids in understanding fundamental cellular mechanisms.

Neuroscience and Cell Signaling

PF-573228 serves as a research reagent for exploring the role of FAK in neuroscience, particularly in neuronal development and function, and in broader cell signaling pathways. Its application helps elucidate complex biological networks.

02 /Properties

Molecular weight	491.49
Empirical formula	C22H20F3N5O3S
Assay	≥95% (HPLC)
Form	powder
Colour	white to off-white
Solubility	DMSO: ≥20 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed
H319Causes serious eye irritation

Precautionary statements

P301IF SWALLOWED
P305IF IN EYES

Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25-36
Safety statements (S)	26-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

869288-64-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is PF-573228 used for?

PF-573228 is used as a research chemical, primarily as an inhibitor of Focal Adhesion Kinase (FAK), aiding studies in cell biology, cell signaling, and neuroscience.

What are the CAS number and formula for PF-573228?

The CAS number for PF-573228 is 869288-64-2, and its molecular formula is C22H20F3N5O3S.

What grade and purity does Tech Serve Solutions supply for PF-573228?

Tech Serve Solutions supplies PF-573228 with a purity of ≥95% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.

How should PF-573228 be handled safely?

PF-573228 is classified as Danger, with hazards including H301 (Toxic if swallowed) and H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment in a well-ventilated area, and seek immediate medical attention if swallowed or if irritation occurs. Refer to the Safety Data Sheet for detailed guidance.

How is PF-573228 packed and shipped?

PF-573228 is stored at 2-8°C and is typically supplied as a powder. As a chemical supplier and exporter, TSS adheres to strict regulations for packing and shipping hazardous materials internationally.

How can I request a quote or sample of PF-573228?

To request a quote or a sample of PF-573228, please contact our sales department via the website or direct email, providing your contact details and intended research application.