n-Dodecyl β-D-glucopyranoside
n-Dodecyl β-D-glucopyranoside (CAS: 59122-55-3, C18H36O6) is a non-ionic detergent with a molecular weight of 348.47 g/mol. It is widely recognised for its utility in biochemical research and diagnostics. This compound is particularly valuable for solubilising membrane proteins, enabling their study and purification in a native-like state. Its applications extend to various biological assays and purification processes.
- IUPAC
- Dodecyl glucoside
- Synonyms
- Dodecyl glucoside

Membrane Protein Solubilization
n-Dodecyl β-D-glucopyranoside is extensively used to gently solubilise integral and peripheral membrane proteins from cellular membranes. Its non-ionic nature helps maintain protein structure and biological activity during extraction and purification processes.
Biochemical Assays
This detergent serves as a crucial component in various biochemical assays, including enzyme activity studies and protein-ligand binding experiments. It aids in creating a suitable environment for biomolecules to function and interact.
Protein Purification
It is employed in chromatographic techniques for the purification of membrane proteins. Its detergent properties facilitate the separation and isolation of target proteins from complex biological mixtures.
Cell Lysis
n-Dodecyl β-D-glucopyranoside can be used for cell lysis, particularly when gentle disruption is required to extract specific cellular components without damaging sensitive biomolecules.
| Molecular weight | 348.47 |
|---|---|
| Empirical formula | C18H36O6 |
| Assay | ≥98% (GC) |
| Solubility | methanol: soluble50 mg/mL, clear to very slightly hazy, colorless |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | non-ionic |
|---|---|
| Cmc | 0.13 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is n-Dodecyl β-D-glucopyranoside used for?
+
n-Dodecyl β-D-glucopyranoside is primarily used for solubilising membrane proteins, in biochemical assays, protein purification, and cell lysis due to its properties as a non-ionic detergent.
What is the CAS number and formula for n-Dodecyl β-D-glucopyranoside?
+
The CAS number is 59122-55-3 and the empirical formula is C18H36O6.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies n-Dodecyl β-D-glucopyranoside with an assay of ≥98% (GC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should n-Dodecyl β-D-glucopyranoside be handled?
+
Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. In case of eye contact, rinse cautiously with water for several minutes. P261-P305 + P351 + P338.
Is n-Dodecyl β-D-glucopyranoside a controlled substance?
+
Based on the provided data, n-Dodecyl β-D-glucopyranoside is not listed as a controlled substance. Further checks may be required depending on your jurisdiction.
How is n-Dodecyl β-D-glucopyranoside packed and exported by TSS?
+
n-Dodecyl β-D-glucopyranoside is packed according to industry standards to ensure stability and safety during transport. As a global supplier, TSS exports this chemical worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for n-Dodecyl β-D-glucopyranoside?
+
To request a sample or a quote, please contact our sales department through the TSS website or by calling our customer service line, providing the product name and CAS number (59122-55-3).
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis