Paromomycin sulfate salt

CAS 1263-89-4C23H45N5O14 · H2SO4Biochemicals & Reagents

Paromomycin sulfate salt (CAS: 1263-89-4), with empirical formula C23H45N5O14 · H2SO4 and a molecular weight of 713.71, is a broad-spectrum aminoglycoside antibiotic. Produced by <i>Streptomyces rimosus var. paromomycinus</i>, it exhibits activity similar to neomycin against Gram-negative and Gram-positive bacteria, as well as certain protozoan species. It is also used in research to investigate bacterial protein synthesis and assembly.

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Paromomycin sulfate salt (C23H45N5O14 · H2SO4) — chemical structure, CAS 1263-89-4; Life Science, fine chemical supplied by Tech Serve Solutions

AminoglycosidesAntibacterialAntibioticsAntibiotics A to ZAntibiotics N-SAntibiotics by ApplicationBiochemicals and ReagentsChemical Structure ClassGenetic Marker SelectionMechanism of Action

01 /Applications

Antibiotic Research

Paromomycin sulfate salt can be used to study bacterial protein synthesis, focusing on the 16S ribosomal RNA and 30S ribosome assembly. Its mechanism involves interfering with these crucial cellular processes.

Cell Culture Studies

This compound has been tested in plant cell culture. It can also be employed in research to investigate specific cellular interactions, such as the inhibition of <i>Cryptosporidium</i> infection in human enterocyte cell lines.

Molecular Biology Research

Paromomycin sulfate salt is utilised in molecular biology research to study cytosine-cytosine (CC) mismatch-containing RNA molecules, providing insights into RNA structure and function.

02 /Properties

Molecular weight	713.71
Empirical formula	C23H45N5O14 · H2SO4
Application	Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against Gram-negative bacteria, Gram-positive bacteria, some protozoan species, and limited antihelminth. It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules1 and is used to inhibit Cryptosporidium infection of a human enterocyte cell line2.
Suitability	plant cell culture tested

03 /Identifiers & registry

CAS number

1263-89-4

MDL number

MFCD00079278

PubChem substance

24278662

Beilstein registry

5715182

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Paromomycin sulfate salt used for?

Paromomycin sulfate salt is used in research to study bacterial protein synthesis and ribosome assembly, to investigate CC mismatch-containing RNA molecules, and to inhibit certain parasitic infections in cell culture models.

What are the CAS number and formula for Paromomycin sulfate salt?

The CAS number for Paromomycin sulfate salt is 1263-89-4, and its empirical formula is C23H45N5O14 · H2SO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Paromomycin sulfate salt as a research-grade chemical. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Paromomycin sulfate salt be handled?

Paromomycin sulfate salt is classified under GHS with a Water Hazard Class (WGK) of 3 in Germany, indicating it is hazardous to aquatic life. Handle with appropriate personal protective equipment in a well-ventilated area.

How is Paromomycin sulfate salt shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Paromomycin sulfate salt, adhering to all relevant shipping and export regulations.

How can I request a sample or quote for Paromomycin sulfate salt?

Please contact the Tech Serve Solutions sales team directly via our website or by phone to request a sample or a detailed quotation for Paromomycin sulfate salt.