Paroxetine hydrochloride hemihydrate
Paroxetine hydrochloride hemihydrate (CAS: 110429-35-1), a selective serotonin reuptake inhibitor (SSRI), is supplied by TSS with a molecular weight of 374.83 g/mol and the formula C19H20FNO3 · HCl · .5 H2O. It is a white powder used primarily in research for its well-documented biological activity, serving as a valuable tool in neuroscience and cell biology studies.
- IUPAC
- (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride hemihydrate

Neuroscience Research
Utilised in studies investigating neurotransmitter pathways, particularly serotonin reuptake mechanisms. Its selective action makes it a key compound for understanding neuronal signalling and related disorders.
Pharmacological Research
Serves as a reference compound in drug discovery and development, aiding in the screening and evaluation of new therapeutic agents. Its known efficacy profiles offer a benchmark for comparative studies.
Cell Biology Studies
Employed to investigate cellular responses to serotonin modulation. This research helps elucidate the role of serotonin in various cellular processes and disease states.
| Molecular weight | 374.83 |
|---|---|
| Empirical formula | C19H20FNO3 · HCl · .5 H2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Paroxetine hydrochloride hemihydrate used for?
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Paroxetine hydrochloride hemihydrate is primarily used in research settings, particularly in neuroscience and cell biology, to study serotonin reuptake inhibition and its effects on neuronal signalling.
What are the CAS number and formula for Paroxetine hydrochloride hemihydrate?
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The CAS number is 110429-35-1, and the formula is C19H20FNO3 · HCl · .5 H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Paroxetine hydrochloride hemihydrate with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should Paroxetine hydrochloride hemihydrate be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified as harmful if swallowed and causes skin and eye irritation (H302, H315, H319, H335).
How is Paroxetine hydrochloride hemihydrate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of shipping and exporting Paroxetine hydrochloride hemihydrate worldwide.
How can I request a sample or quote?
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To request a sample or obtain a quotation for Paroxetine hydrochloride hemihydrate, please contact our sales team directly through our website or by phone.
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