Pefloxacin mesylate dihydrate
Pefloxacin mesylate dihydrate (CAS: 149676-40-4) is a synthetic fluoroquinolone antibiotic with broad-spectrum activity against gram-positive and gram-negative bacteria. Its chemical formula is C17H20FN3O3 • CH4O3S • 2H2O and it has a molecular weight of 465.49 g/mol. This compound is utilised in treating specific bacterial infections and as a research tool to study antibiotic-induced toxicity, such as tendon damage in preclinical models.
- IUPAC
- 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate,Pefloxacine monomethanesulfonate dihydrate,Pefloxacinium methanesulfonate dihydrate
- Synonyms
- Pefloxacine monomethanesulfonate dihydratePefloxacinium methanesulfonate dihydrate
Antibacterial Agent
Pefloxacin mesylate dihydrate functions as a synthetic broad-spectrum fluoroquinolone antibiotic. It is employed to combat infections caused by most gram-negative and gram-positive bacterial strains.
Research Tool for Toxicity Studies
This compound has been utilised in preclinical research to induce and study achilles tendon toxicity in rodent models. Its cytotoxicity and uptake mechanisms in hepatic cells have also been investigated.
Treatment of Genitourinary and Gastrointestinal Infections
It is indicated for treating gram-negative bacterial infections affecting the gastrointestinal system and the genitourinary tract. It has also been used for gonococcal urethritis.
| Molecular weight | 465.49 |
|---|---|
| Linear formula | C17H20FN3O3 • CH4O3S • 2H2O |
| Storage temperature | 2-8°C |
| Application | Pefloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic that is effective against most gram-negative and gram-positive bacteria. It is used to treat gonococcal urethritis and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract. Pefloxacin mesylate dihydrate has been used to induce achilles tendon toxicity in rodents1. It′s cytotoxicity and uptake has been studied in primary cultures of rat hepatocytes2. |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pefloxacin mesylate dihydrate used for?
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Pefloxacin mesylate dihydrate is used as a broad-spectrum antibiotic to treat certain bacterial infections, including those in the gastrointestinal and genitourinary tracts, and gonococcal urethritis. It is also used in research to study antibiotic-induced toxicity, such as tendon damage.
What is the CAS number and chemical formula for Pefloxacin mesylate dihydrate?
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The CAS number is 149676-40-4 and the chemical formula is C17H20FN3O3 • CH4O3S • 2H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pefloxacin mesylate dihydrate suitable for research and laboratory use. The specific assay and purity details are available upon request, and TSS does not represent this product as USP, BP, or EP grade.
How should Pefloxacin mesylate dihydrate be handled?
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Pefloxacin mesylate dihydrate is classified as a Warning with Hazard Statement H319 (Causes serious eye irritation). It requires handling with appropriate personal protective equipment, including dust mask type N95, eyeshields, and gloves. Ensure good ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes.
Is Pefloxacin mesylate dihydrate a controlled substance?
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Based on the provided data, Pefloxacin mesylate dihydrate is not indicated as a controlled substance. However, users should always comply with local regulations regarding its use and handling.
How is Pefloxacin mesylate dihydrate packed and shipped?
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Pefloxacin mesylate dihydrate is typically stored at 2-8°C. TSS exports fine chemicals globally, adhering to all necessary shipping regulations for hazardous materials. Specific packing configurations are available based on order requirements.
How can I request a quote or sample for Pefloxacin mesylate dihydrate?
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To request a quote or sample for Pefloxacin mesylate dihydrate, please contact our sales team through the website or by phone, providing your details and the quantity required.
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