1H-Pyrazole-4-boronic acid
1H-Pyrazole-4-boronic acid (CAS 763120-58-7), with the molecular formula C3H5BN2O2 and a molecular weight of 111.90 g/mol, is a key building block in organic synthesis. This compound is frequently employed in cross-coupling reactions, particularly Suzuki-Miyaura couplings, for the construction of complex molecules. It is an indispensable reagent for researchers in medicinal chemistry and materials science seeking to introduce the pyrazole moiety into target structures.
- IUPAC
- 4-Pyrazoleboronic acid,Pyrazol-4-ylboronic acid
- Synonyms
- 4-Pyrazoleboronic acidPyrazol-4-ylboronic acid
Suzuki-Miyaura Coupling Reagent
Utilised as a coupling partner in palladium-catalysed Suzuki-Miyaura reactions for the formation of carbon-carbon bonds. This enables the synthesis of biaryl compounds and complex heterocyclic structures.
Medicinal Chemistry Intermediate
Serves as a vital intermediate in the synthesis of novel pharmaceutical agents. The pyrazole core is a common scaffold found in many biologically active compounds.
Materials Science
Incorporated into the design and synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) and other functional organic materials, owing to the electronic properties of the pyrazole ring.
Organic Synthesis Building Block
A versatile building block for introducing the 4-pyrazolyl group into various organic molecules. It is useful for creating diverse chemical libraries for drug discovery and development.
| Molecular weight | 111.90 |
|---|---|
| Empirical formula | C3H5BN2O2 |
| Assay | ≥95.0% |
| Storage temperature | 2-8°C |
| Application | May contain varying amounts of anhydride |
| Melting point | 146-151 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1H-Pyrazole-4-boronic acid used for?
+
1H-Pyrazole-4-boronic acid is primarily used as a coupling partner in Suzuki-Miyaura reactions for synthesising complex organic molecules, including pharmaceutical intermediates and materials for organic electronics.
What is the CAS number and formula for 1H-Pyrazole-4-boronic acid?
+
The CAS number is 763120-58-7 and the empirical formula is C3H5BN2O2.
What grade and purity does Tech Serve Solutions supply for 1H-Pyrazole-4-boronic acid?
+
Tech Serve Solutions supplies 1H-Pyrazole-4-boronic acid with an assay of ≥95.0%. This product is suitable for research and synthesis purposes and is not supplied as USP, BP, or EP grade.
How should 1H-Pyrazole-4-boronic acid be handled and stored?
+
Handle with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. It is recommended to store at 2-8°C. The compound is an irritant to the skin, eyes, and respiratory tract (H315-H319-H335).
How is 1H-Pyrazole-4-boronic acid packed and exported?
+
1H-Pyrazole-4-boronic acid is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.
How can I request a sample or quote for 1H-Pyrazole-4-boronic acid?
+
To request a sample or a quotation, please contact our sales department via the website or direct email, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis