Pargyline hydrochloride
Pargyline hydrochloride (CAS: 306-07-0), with the chemical formula C6H5CH2N(CH3)CH2C≡CH·HCl and a molecular weight of 195.69 g/mol, is a bioactive small molecule. It functions as an irreversible inhibitor of monoamine oxidase B (MAO-B). This compound is primarily utilised in biochemical research for investigating enzyme activity and cellular signalling pathways, particularly within neuroscience and epigenetic studies.
- IUPAC
- N-Methyl-N-(2-propynyl)benzylamine hydrochloride,N-Methyl-N-propargylbenzylamine hydrochloride
- Synonyms
- N-Methyl-N-(2-propynyl)benzylamine hydrochlorideN-Methyl-N-propargylbenzylamine hydrochloride

MAO-B Inhibition Research
Pargyline hydrochloride serves as a selective and irreversible inhibitor of monoamine oxidase B. It is widely employed in laboratory settings to study the role of MAO-B in neurotransmitter metabolism and neurological processes.
Neuroscience Studies
This compound is valuable for research in neuroscience, aiding investigations into the functions of enzymes involved in the breakdown of monoamines, such as dopamine, and their impact on brain function.
Epigenetic Research Tool
As a bioactive small molecule, Pargyline hydrochloride finds application in epigenetic research, potentially influencing cellular mechanisms related to gene expression and regulation.
| Molecular weight | 195.69 |
|---|---|
| Linear formula | C6H5CH2N(CH3)CH2C≡CH·HCl |
| Storage temperature | −20°C |
| Melting point | 160-163 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... MAOB(4129) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pargyline hydrochloride used for?
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Pargyline hydrochloride is used in biochemical research as an irreversible inhibitor of monoamine oxidase B (MAO-B), aiding studies in neuroscience and epigenetics.
What are the CAS number and chemical formula for Pargyline hydrochloride?
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The CAS number is 306-07-0, and the chemical formula is C6H5CH2N(CH3)CH2C≡CH·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pargyline hydrochloride as a research-grade chemical. Specific purity details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should Pargyline hydrochloride be handled safely?
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Pargyline hydrochloride is classified as toxic if swallowed (H301) and requires careful handling. Wear appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves. Avoid dust formation and inhalation.
How is Pargyline hydrochloride shipped and exported?
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Pargyline hydrochloride is shipped and exported in compliance with international regulations for hazardous materials, adhering to UN 2811, Class 6.1, Packing Group III.
How can I request a sample or quote for Pargyline hydrochloride?
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To request a sample or a quote for Pargyline hydrochloride, please contact our sales department via the website or email, providing your contact details and desired quantity.
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