4-Bromo-1-butyne
4-Bromo-1-butyne (CAS 38771-21-0), with the molecular formula C4H5Br and a molecular weight of 132.99 g/mol, is a valuable organic building block. This terminal alkyne features a reactive bromine atom and a triple bond, making it useful in diverse synthetic pathways. It is primarily employed in chemical synthesis for the introduction of the 3-butynyl group in complex molecule construction and pharmaceutical intermediate development.
- IUPAC
- 1-Bromo-3-butyne
- Synonyms
- 1-Bromo-3-butyne
Organic Synthesis Intermediate
4-Bromo-1-butyne serves as a key intermediate in the synthesis of more complex organic molecules. Its bifunctional nature allows for selective reactions at either the alkyne or the alkyl halide moiety.
Pharmaceutical Research
This compound is utilised in the development of novel pharmaceutical agents. It can be incorporated into molecular frameworks during the early stages of drug discovery and process research.
Material Science
The reactivity of 4-Bromo-1-butyne can be leveraged in the creation of specialised polymers and functionalised materials, contributing to advancements in material science.
| Molecular weight | 132.99 |
|---|---|
| Empirical formula | C4H5Br |
| Assay | 97% |
| Density | 1.417 g/mL at 25 °C |
| Refractive index | n20/D 1.481 |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 23 °C / 73.4 °F |
| Transport (UN / ADR) | UN 1992 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-25-43 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-1-butyne primarily used for?
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4-Bromo-1-butyne is primarily used as an intermediate in organic synthesis, particularly for constructing complex molecules in pharmaceutical research and development.
What is the CAS number and molecular formula for 4-Bromo-1-butyne?
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The CAS number for 4-Bromo-1-butyne is 38771-21-0, and its molecular formula is C4H5Br.
What grade and purity does Tech Serve Solutions supply for 4-Bromo-1-butyne?
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Tech Serve Solutions supplies 4-Bromo-1-butyne with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 4-Bromo-1-butyne be handled safely?
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4-Bromo-1-butyne is a flammable liquid and vapour (H226) and is toxic if swallowed (H301) and may cause an allergic skin reaction (H317). Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Work in a well-ventilated area and avoid ignition sources.
How is 4-Bromo-1-butyne shipped and exported?
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4-Bromo-1-butyne is classified as UN 1992, Hazard Class 3, Packing Group III (Flammable Liquid). It is shipped and exported in compliance with international regulations for hazardous materials.
How can I request a quote or sample of 4-Bromo-1-butyne?
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To request a quote or a sample of 4-Bromo-1-butyne, please contact the Tech Serve Solutions sales team through our website or by phone.
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