Palmitic acid N-hydroxysuccinimide ester
Palmitic acid N-hydroxysuccinimide ester (CAS: 14464-31-4; Formula: C20H35NO4) is a valuable biochemical reagent. With a molecular weight of 353.50 g/mol, it functions as an activated ester of palmitic acid. This compound is primarily utilised in organic synthesis for the introduction of the hexadecanoyl (palmitoyl) group onto various nucleophiles, including amino acids and thiols. It is supplied by Tech Serve Solutions with an assay of ≥98% (TLC) and stored at -20°C.
- IUPAC
- N-(Palmitoyloxy)succinimide,N-Succinimidyl palmitate,Palmitic acid N-succinimidyl ester
- Synonyms
- N-(Palmitoyloxy)succinimideN-Succinimidyl palmitatePalmitic acid N-succinimidyl ester

Synthesis of Hexadecanoyl Derivatives
This reagent is employed to attach the hexadecanoyl moiety to molecules containing amino or thiol groups. This is particularly useful in the modification of amino acids and thioglycolic acid.
Bioconjugation and Labelling
It can be used in research settings for labelling peptides, proteins, or other biomolecules with a palmitoyl chain. This modification can influence lipophilicity and membrane association.
Preparation of Acylamino Acids
The ester facilitates the formation of N-acylated amino acids, which are important intermediates in peptide synthesis or can have biological roles themselves.
| Molecular weight | 353.50 |
|---|---|
| Empirical formula | C20H35NO4 |
| Assay | ≥98% (TLC) |
| Storage temperature | −20°C |
| Application | Useful in the synthesis of hexadecanoyl derivatives of amino- and thio-compounds such as amino acids, aminoacyl-tRNA, coenzyme A, thioglycolic acid, etc. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Palmitic acid N-hydroxysuccinimide ester used for?
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Palmitic acid N-hydroxysuccinimide ester is useful in the synthesis of hexadecanoyl derivatives of amino- and thio-compounds such as amino acids, aminoacyl-tRNA, coenzyme A, and thioglycolic acid.
What is the CAS number and formula for Palmitic acid N-hydroxysuccinimide ester?
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The CAS number is 14464-31-4, and the molecular formula is C20H35NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Palmitic acid N-hydroxysuccinimide ester with an assay of ≥98% (TLC). This is a technical/research grade material; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should Palmitic acid N-hydroxysuccinimide ester be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C to maintain stability.
Is this product a controlled substance?
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The provided data does not indicate that Palmitic acid N-hydroxysuccinimide ester is a controlled substance.
How can I request a sample or quote for Palmitic acid N-hydroxysuccinimide ester?
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Please contact the TSS sales team via our website or direct inquiry channels to request a sample or a quotation for Palmitic acid N-hydroxysuccinimide ester.
How is Palmitic acid N-hydroxysuccinimide ester packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for chemical stability and safety during transit, adhering to international shipping regulations for chemical products.
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