PTIO
PTIO (CAS: 18390-00-6), with the molecular formula C13H17N2O2, is a nitroxyl radical primarily used as a nitric oxide (NO) scavenger and spin trap. It is a valuable reagent in biochemical and cell biology research, particularly for studying NO metabolism and its role in cellular signaling and stress responses. This compound aids in the detection and quantification of NO radicals, making it indispensable for understanding various physiological and pathological processes.
- IUPAC
- 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide
- Synonyms
- 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide
Nitric Oxide Scavenging
PTIO effectively scavenges nitric oxide (NO) radicals, making it a crucial tool for investigating the biological roles of NO in physiological and pathological conditions. Its reaction with NO allows for the study of NO signaling pathways.
Spin Trapping in EPR Spectroscopy
As a stable nitroxyl radical, PTIO can function as a spin trap in electron paramagnetic resonance (EPR) spectroscopy. This application is vital for detecting and characterizing short-lived radical species generated in biological systems.
Cell Biology Research
This compound is widely employed in cell biology to probe the involvement of nitric oxide in cellular processes such as inflammation, apoptosis, and cell proliferation. It helps researchers understand NO's impact on cell viability and function.
Biochemical Assays
PTIO serves as a reagent in various biochemical assays designed to measure NO production or its effects. It is instrumental in studying enzymes involved in NO metabolism and in assessing oxidative stress.
| Molecular weight | 233.29 |
|---|---|
| Empirical formula | C13H17N2O2 |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PTIO used for?
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PTIO is primarily used as a nitric oxide (NO) scavenger and spin trap in biochemical and cell biology research. It aids in studying NO metabolism, NO signaling pathways, and detecting free radicals using EPR spectroscopy.
What is the CAS number and formula for PTIO?
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The CAS number for PTIO is 18390-00-6, and its molecular formula is C13H17N2O2.
What grade and purity does Tech Serve Solutions supply for PTIO?
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Tech Serve Solutions supplies PTIO for research and laboratory use. The specific assay and purity are detailed on the product page. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should PTIO be handled safely?
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PTIO is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area.
How is PTIO packed and shipped by TSS?
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Tech Serve Solutions professionally packs and ships PTIO, adhering to all necessary regulations for the transport of chemical reagents. We are a global supplier and exporter.
How can I request a sample or quote for PTIO?
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To request a sample or a quote for PTIO, please use the contact form on our website or reach out to our sales department directly.
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