p-Fluoro-D-phenylalanine
p-Fluoro-D-phenylalanine (CAS: 18125-46-7; Formula: C9H10FNO2; Molar Mass: 183.18 g/mol) is an unnatural amino acid derivative. It functions as a valuable building block in chemical synthesis and peptide chemistry. Its unique fluorinated structure offers altered electronic and steric properties, making it useful in chemical biology research for probing biological systems and developing novel peptide-based therapeutics.
- IUPAC
- 4-Fluoro-D-phenylalanine
Chemical Biology Research
Incorporated into peptides and proteins to study structure-activity relationships and probe biological mechanisms. The fluorine atom can serve as a useful NMR probe.
Peptide Synthesis
Used as a non-canonical amino acid to create modified peptides with altered stability, binding affinity, or pharmacological properties.
Drug Discovery Intermediate
Serves as a key intermediate in the synthesis of novel pharmaceutical candidates where fluorination can enhance metabolic stability or target binding.
Chemical Synthesis Building Block
A versatile precursor for creating complex organic molecules and fluorinated compounds in various synthetic pathways.
| Molecular weight | 183.18 |
|---|---|
| Empirical formula | C9H10FNO2 |
| Assay | ≥99.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D +23±2°, c = 1% in H2O |
| Optical purity | enantiomeric ratio: ≥99:1 (TLC) |
| Melting point | ~245 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Fluoro-D-phenylalanine used for?
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p-Fluoro-D-phenylalanine is used in chemical biology research, peptide synthesis, as an intermediate in drug discovery, and as a general building block in chemical synthesis.
What is the CAS number and chemical formula for p-Fluoro-D-phenylalanine?
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The CAS number is 18125-46-7, and the chemical formula is C9H10FNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Fluoro-D-phenylalanine with an assay of ≥99.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for p-Fluoro-D-phenylalanine?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Refer to the Safety Data Sheet for comprehensive information.
Is p-Fluoro-D-phenylalanine a controlled substance?
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The provided data does not indicate that p-Fluoro-D-phenylalanine is a controlled substance.
How can I request a sample or quote for p-Fluoro-D-phenylalanine?
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Please contact our sales team via the website or your dedicated account manager to request a sample or a formal quotation.
How is p-Fluoro-D-phenylalanine shipped?
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We export and ship chemicals globally, adhering to all relevant transport regulations. Please contact us for specific shipping details to your region.
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