p-Formylbenzoic acid N-hydroxysuccinimide ester
p-Formylbenzoic acid N-hydroxysuccinimide ester (CAS: 60444-78-2) is a key organic building block with the molecular formula C12H9NO5 and a molecular weight of 247.20 g/mol. This compound functions as an activated ester, facilitating facile coupling reactions. It is particularly useful in chemical synthesis for introducing the formylbenzoyl moiety onto various substrates, making it valuable in the development of complex organic molecules and pharmaceutical intermediates.
- IUPAC
- N-Succinimidyl 4-formylbenzoate
Organic Synthesis Reagent
Utilised as an activated ester and an organic building block, this compound is instrumental in diverse synthetic pathways. Its structure allows for efficient conjugation, making it suitable for introducing specific functional groups in multi-step syntheses.
Pharmaceutical Intermediate Development
The molecule serves as a valuable intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its reactive nature enables the controlled construction of complex molecular architectures relevant to drug discovery and development.
Bioconjugation Applications
As a reactive carbonyl compound, it can be employed in bioconjugation strategies to modify biomolecules. This ester functionality is amenable to reactions with nucleophiles found in proteins and other biological entities.
| Molecular weight | 247.20 |
|---|---|
| Empirical formula | C12H9NO5 |
| Assay | ≥97.0% (HPLC) |
| Solubility | methanol: soluble50 mg/mL, clear to very faintly turbid, colorless |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Formylbenzoic acid N-hydroxysuccinimide ester used for?
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p-Formylbenzoic acid N-hydroxysuccinimide ester is primarily used as an organic building block and reagent in chemical synthesis, particularly for introducing the formylbenzoyl moiety, and as an intermediate in pharmaceutical development and bioconjugation.
What is the CAS number and chemical formula for p-Formylbenzoic acid N-hydroxysuccinimide ester?
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The CAS number is 60444-78-2, and the chemical formula is C12H9NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Formylbenzoic acid N-hydroxysuccinimide ester with a purity of ≥97.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling this compound?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a significant hazard to water.
How is this chemical supplied and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packaging and shipping details are available upon request for international orders.
How can I request a quote or sample?
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To request a quote or sample of p-Formylbenzoic acid N-hydroxysuccinimide ester, please contact the Tech Serve Solutions sales team through our website or direct contact details.
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