p-Fluoro-DL-phenylalanine
p-Fluoro-DL-phenylalanine (CAS: 51-65-0) is a fluorinated unnatural amino acid derivative with the linear formula FC₆H₄CH₂CH(NH₂)COOH and a molecular weight of 183.18 g/mol. This compound is valuable in chemical biology and synthesis, particularly within peptide chemistry. It serves as a building block for creating novel peptides and proteins with altered properties, enabling research into structure-function relationships and the development of new biochemical tools.
Chemical Biology Research
Used as a tool in chemical biology to investigate protein structure, function, and interactions. Its incorporation into peptides can alter their biophysical and biological characteristics, aiding in the study of biological processes.
Peptide Synthesis
Serves as a non-canonical amino acid in solid-phase or solution-phase peptide synthesis. It allows for the introduction of a fluorine atom into peptide sequences, which can enhance metabolic stability or probe binding sites.
Drug Discovery and Development
Can be employed in the synthesis of novel pharmaceutical intermediates or drug candidates. The fluorine substitution may influence pharmacokinetic properties, such as lipophilicity and metabolic stability.
Biochemical Probes
Incorporated into peptides or proteins to act as a probe for NMR studies or other biophysical analyses. The fluorine atom can serve as an NMR reporter nucleus.
| Molecular weight | 183.18 |
|---|---|
| Linear formula | FC6H4CH2CH(NH2)COOH |
| Assay | ≥99.0% (NT) |
| Melting point | 253-255 °C (dec.)(lit.)~270 °C (dec.) |
Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Fluoro-DL-phenylalanine used for?
+
p-Fluoro-DL-phenylalanine is primarily used in chemical biology research, peptide synthesis, drug discovery, and as a biochemical probe. It serves as a building block for creating modified peptides and proteins.
What is the CAS number and chemical formula for p-Fluoro-DL-phenylalanine?
+
The CAS number is 51-65-0, and its linear formula is FC₆H₄CH₂CH(NH₂)COOH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies p-Fluoro-DL-phenylalanine with an assay of ≥99.0% (NT). This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should p-Fluoro-DL-phenylalanine be handled safely?
+
p-Fluoro-DL-phenylalanine is classified as acutely toxic if swallowed (H300) and requires careful handling. Use in a well-ventilated area with appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges. In case of accidental ingestion, seek immediate medical attention.
How is p-Fluoro-DL-phenylalanine packed and exported by TSS?
+
p-Fluoro-DL-phenylalanine is packed in accordance with UN 2811, Class 6.1, Packing Group III regulations for safe transport. TSS exports this chemical globally, adhering to all relevant shipping and handling regulations.
How can I request a sample or quote for p-Fluoro-DL-phenylalanine?
+
To request a sample or quote, please use the contact form on our website or reach out to our sales team directly. Please specify the required quantity and your delivery location.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis