p-Coumaric acid
p-Coumaric acid (CAS: 501-98-4) is a hydroxycinnamic acid derivative with the molecular formula HOC₆H₄CH=CHCO₂H and a molecular weight of 164.16 g/mol. This compound is naturally occurring and found in various plants. It is recognised for its antioxidant properties and serves as a valuable building block in chemical synthesis and research applications.
- IUPAC
- trans-4-Hydroxycinnamic acid
- Synonyms
- trans-4-Hydroxycinnamic acid

Chemical Synthesis
p-Coumaric acid serves as a precursor and intermediate in the synthesis of more complex organic molecules. Its reactive functional groups allow for various chemical modifications in research and development settings.
Research Reagent
Utilised in biochemical and cell biology studies, p-Coumaric acid aids in investigating biological pathways and the effects of phenolic compounds. It is a useful reagent for laboratory research.
Building Block
As a fundamental organic compound, p-Coumaric acid acts as a building block for constructing diverse chemical structures in academic and industrial research laboratories.
| Molecular weight | 164.16 |
|---|---|
| Linear formula | HOC6H4CH=CHCO2H |
| Assay | ≥98.0% (HPLC) |
| Grade | purum |
| Solubility | ethanol: soluble50 mg/mL |
| Melting point | 214 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shelf Life | (limited shelf life, expiry date on the label) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Coumaric acid used for?
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p-Coumaric acid is used as a building block in chemical synthesis and as a reagent in biochemical and cell biology research. It is found naturally in various plants.
What are the CAS number and formula for p-Coumaric acid?
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The CAS number for p-Coumaric acid is 501-98-4, and its linear formula is HOC₆H₄CH=CHCO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Coumaric acid in purum grade with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should p-Coumaric acid be handled safely?
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p-Coumaric acid is classified with GHS07 symbol and a 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask (type N95), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust.
Is p-Coumaric acid a controlled substance?
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The provided data does not indicate that p-Coumaric acid is a controlled substance.
How is p-Coumaric acid packed and shipped?
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p-Coumaric acid is supplied with limited shelf life, and the expiry date is indicated on the label. Specific packing and shipping details for export are available upon request.
How can I request a sample or a quote for p-Coumaric acid?
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To request a sample or a quote for p-Coumaric acid, please contact our sales department via the website or your designated sales representative.
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